Results 91 to 100 of about 29,806 (309)

Large-scale screening of HCMV-seropositive blood donors indicates that HCMV effectively escapes from antibodies by cell-associated spread [PDF]

, 2018
Immunoglobulins are only moderately effective for the treatment of human cytomegalovirus (HCMV) infections, possibly due to ineffectiveness against cell-associated virus spread.
Alt, Mira, Falk, Jessica, Krawczyk, Adalbert, Laib Sampaio, Kerstin, Lotfi, Ramin, Paal, Caroline, Schrezenmeier, Hubert, Sinzger, Christian, Stanton, Richard, Winkelmann, Martina   +9 more
core   +2 more sources

Smart Face Masks as Wearable Respiratory Sensors: A Review of Sensor Technologies, Materials, and Future Directions

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in smart face masks that actively monitor breathing. By integrating humidity, gas, temperature, pressure, strain, and triboelectric sensors, these masks track key respiratory parameters in real time. The article summarizes sensor mechanisms, compares performance across studies, and discusses challenges and future ...
Negin Faramarzi, Naseeh Backer Kannanthodi, Alice Nicole Casling, Babar Ali, Samira Lakouraj Mansouri, Alessandro Giuseppe D'aloia, Hossein Cheraghi Bidsorkhi, Maria Sabrina Sarto   +7 more
wiley   +1 more source

Direct-acting antivirals for RSV treatment, a review

Antiviral Research
Respiratory syncytial virus (RSV) causes respiratory disease and complications in infants, the elderly and the immunocompromised. While three vaccines and two prophylactic monoclonal antibodies are now available, only one antiviral, ribavirin, is currently approved for treatment.
Brecht Bonneux, Edgar Jacoby, Martina Ceconi, Kim Stobbelaar, Peter Delputte, Florence Herschke   +5 more
openaire   +3 more sources

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Curing Hepatitis C in Liver Transplant Recipients Is Associated with Changes in Immunosuppressant Use. [PDF]

, 2016
Background and aimsAll-oral interferon-free antivirals are highly effective in treating recurrent hepatitis C (HCV) infection in liver transplant (LT) recipients.
Bau, Sherona, Busuttil, Ronald W, Choi, Gina, Durazo, Francisco, El Kabany, Mohammed, Elashoff, David, Farid, Alexander, Grotts, Jonathan, Han, Steven, Jamal, Naadir, Jimenez, Melissa, Rheem, Justin, Saab, Sammy   +12 more
core   +2 more sources

Combination interventions to prevent HCV transmission among people who inject drugs: modelling the impact of antiviral treatment, needle and syringe programs, and opiate substitution therapy [PDF]

, 2013
BackgroundInterventions such as opiate substitution therapy (OST) and high-coverage needle and syringe programs (HCNSP) cannot substantially reduce hepatitis C virus (HCV) prevalence among people who inject drugs (PWID).
Aspinall, Bukten, Cornish, David J. Goldberg, De Angelis, Degenhardt, Dore, Durier, Gane, Grebely, Guinness, Hellard, Hickman, Liu, Lozano, Macarthur, Martin, Martin, Martin, Martin, Matthew Hickman, Micallef, Natasha K. Martin, Nelson, Nordt, Peter Vickerman, Poordad, Sharon J. Hutchinson, Shepard, Sweeting, Turner, Vickerman, Vickerman   +32 more
core   +3 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Profile of alisporivir and its potential in the treatment of hepatitis C

Drug Design, Development and Therapy, 2013
Philippe A Gallay,1 Kai Lin21Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA, 2Permeon Biologics Inc, One Kendall Square, Cambridge, MA, USAAbstract: Two classes of hepatitis C antiviral agents currently exist,
Gallay PA, Lin K
doaj  

Hepatitis C Treatment: A Review and Update

Southeastern European Medical Journal, 2017
Hepatitis C virus infection (HCV) infects approximately 185 million individuals worldwide. It is a leading cause of chronic liver disease and the primary reason for liver transplantation.
Jelena Jakab, Marinko Žulj, Nikola Volarić, Bojan Tepeš, Aleksandar Včev   +4 more
doaj   +1 more source