Results 41 to 50 of about 678,745 (265)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Evolutionary Policy Transfer and Search Methods for Boosting Behavior Quality: RoboCup Keep-Away Case Study

Frontiers in Robotics and AI, 2017
This study evaluates various evolutionary search methods to direct neural controller evolution in company with policy (behavior) transfer across increasingly complex collective robotic (RoboCup keep-away) tasks.
Geoff Nitschke, Sabre Didi
doaj   +1 more source

Faster Capacitated Arc Routing: A Sequence-to-Sequence Approach

IEEE Access, 2022
The Capacitated Arc Routing Problem (CARP) is an NP-hard optimization problem that has been investigated for decades. Heuristic search methods are commonly used to solve it.
Wenjing Hong, Tonglin Liu
doaj   +1 more source

Parallel Optimization Methods Based on Direct Search [PDF]

, 2006
This paper is focused in the parallelization of Direct Search Optimization methods, which are part of the family of derivative-free methods. These methods are known to be quite slow, but are easily parallelizable, and have the advantage of achieving global convergence in some problems where standard Newton-like methods (based on derivatives) fail ...
Rafael A. Trujillo Rasúa, Antonio M. Vidal, Víctor M. García   +2 more
openaire   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Combined domain knowledge and simplified model method for worst-case analysis of deck girder under multiple patch loads

Zhongguo Jianchuan Yanjiu
ObjectiveThis paper proposes a method for improving the efficiency and accuracy of finding the worst-case positions of wheel patch loads on deck grillage.
xiangyun LUO, Jun LIU, Puyu JIANG, yuansheng CHENG   +3 more
doaj   +1 more source

Efficient Local Search in Imaging Optimization Problems with a Hybrid Evolutionary Algorithm [PDF]

Journal of Systemics, Cybernetics and Informatics, 2005
The paper focuses on the efficiency of local search in a Hybrid evolutionary algorithm (HEA), with application to optimization problem frequently encountered in electronic imaging.
Igor Maslov
doaj  

Population-based methods in the optimization of stand management

Silva Fennica, 2009
In Finland, the growth and yield models for tree stands are simulation programs that consist of several sub-models. These models are often non-smooth and non-differentiable.
Pukkala, Timo
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source