Results 151 to 160 of about 3,271,959 (246)
Selective N‐Functionalization of Pyrazoles
European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source
Modular Synthesis of Di‐ and Triazadibenzoazulenes by a Cross‐Coupling/Cycloisomerization Strategy
European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.Two series of regioisomeric di‐ and triazadibenzoazulenes were prepared from dihalogenated imidazo[1,2‐a]pyridines and imidazo[1,2‐a]pyrazines. Imidazo[1,2‐a]pyridines and imidazo[1,2‐a]pyrazines are important nitrogen‐containing heterocycles with applications in medicinal and materials chemistry.
Karyna Kulyk +6 more
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Ag/Pd Cocatalyzed Direct Arylation of Fluoroarene Derivatives with Aryl Bromides. [PDF]
ACS Catal, 2020 Panigrahi A +3 more
europepmc +1 more source
Chiral Pyrazolinylidene Complexes for Asymmetric Catalysis
Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.The synthesis and application of pyrazolin‐5‐ylidene NHC chiral‐at‐ruthenium catalysts is reported. The strong donating pyrazolin‐5‐ylidene ligands led to highly electron rich ruthenium complexes, which showed excellent catalytic activity and enantioselectivity in the intramolecular aziridination of an alkene.
Felix Möller +6 more
wiley +1 more source
Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology
European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau +3 more
wiley +1 more source
Visible‐Light Cobalt‐Catalyzed Synthesis of Aroyl Amides From Arylazo Sulfones
Advanced Synthesis &Catalysis, Volume 368, Issue 20, 16 October 2026.Blue Light and Cobalt Catalysis for Synthesis! A versatile strategy that combines photoactive arylazo sulfones as substrates and Co2(CO)8 as a catalyst for the preparation of aromatic amides is presented herein. A versatile strategy leveraging the peculiar reactivity of arylazo sulfones as substrates bearing dyedauxiliary groups in arylation processes,
Komal Jaiswal +4 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.A new type of Si─Me bond activation enabling catalytic alkyl exchange at Si was developed. It involves a P‐directing group and Pd─Lewis acid cooperation. It enables the conversion of Me3SiCl into silanols with three different organic substituents. ABSTRACT A novel mode of Si─Me bond activation has been unveiled through the cooperative action of a P ...
Hajime Kameo +5 more
wiley +2 more sources
A Direct Arylation Approach for Helicene Analogues Composed of Unidirectional Amide Linkages. [PDF]
ACS OmegaYokoyama A +5 more
europepmc +1 more source
Merging Micellar Catalysis and C-H Activation: Silver-Free Direct Arylation of Fluoroarenes in Water. [PDF]
ChemSusChemBelnome F +9 more
europepmc +1 more source