Results 71 to 80 of about 4,963,210 (228)

Remote Migratory Reductive Arylation of Unactivated Alkenes Enabled by Electrochemical Nickel Catalysis

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
we have developed an electrochemical Ni−H catalyzed arylation coupling method of unactivated alkenes with aryl halides. The method displays broad functional group tolerance and proceeds under very mild conditions. Furthermore, aryl chlorides were also compatible substrates in this catalytic system. This conversion holds significant implications for the
Chao Xu, Ru‐Han A, Xiao‐Feng Wu
wiley   +1 more source

Mono or double Pd-catalyzed C–H bond functionalization for the annulative π-extension of 1,8-dibromonaphthalene: a one pot access to fluoranthene derivatives

Beilstein Journal of Organic Chemistry
The Pd-catalyzed annulative π-extension of 1,8-dibromonaphthalene for the preparation of fluoranthenes in a single operation has been investigated. With specific arenes such as fluorobenzenes, the Pd-catalyzed double functionalization of C–H bonds yields
Nahed Ketata, Linhao Liu, Ridha Ben Salem, Henri Doucet   +3 more
doaj   +1 more source

Recent Developments in the Field of Air‐Stable Nickel(0) Precatalysts for Cross‐Coupling Reactions

European Journal of Inorganic Chemistry, EarlyView.
The development of bench‐stable Ni(0) sources aims to replace air‐sensitive [Ni(COD)2] (cod = cycloocta‐1,5‐diene) with easy‐to‐handle alternatives. Through a targeted ligand design, using electron‐deficient dienes, carbenes, and fluorophosphines, researchers have achieved air‐ and moisture‐tolerant complexes that show high catalytic activity in cross ...
Franziska Flecken, Schirin Hanf
wiley   +1 more source

Structural Features Defining NF-κB Inhibition by Lignan-Inspired Benzofurans and Benzothiophenes

Biomolecules, 2020
A series of 2-arylbenzofurans and 2-arylbenzothiophenes was synthesized carrying three different side chains in position five. The synthesized compounds were tested for NF-κB inhibition to establish a structure activity relationship.
Toan Dao-Huy, Simone Latkolik, Julia Bräuer, Andreas Pfeil, Hermann Stuppner, Michael Schnürch, Verena M. Dirsch, Marko D. Mihovilovic   +7 more
doaj   +1 more source

Heteroaryl‐Substituted Polyfluorobiaryls Synthesis via Palladium‐Catalyzed Double CH Bond Functionalization Using Palladium 1,4‐Migration Associated to Direct Arylation

European Journal of Organic Chemistry, EarlyView.
Fluoro substituents on a benzene ring linked to a 2‐bromoaryl group enables the selective activation of one of its CH bonds via Pd‐1,4‐migration. Then, Pd‐catalyzed direct coupling with heteroarenes produces C2’‐heteroarylated 1,1′‐biaryls. In this reaction, the new C–C bond arises from the functionalization of two CH bonds.
Norman Le Floch, Thierry Roisnel, Henri Doucet   +2 more
wiley   +1 more source

SÍNTESE DE DERIVADOS DE FENANTRIDINONAS POR ARILAÇÃO DIRETA. CARACTERIZAÇÃO DOS ESPECTROS DE ABSORÇÃO E EMISSÃO DE EXEMPLOS REPRESENTATIVOS

Química Nova, 2016
The phenanthridinone heterocyclic system has attracted considerable attention in recent years due to the diverse array of physical, chemical and pharmacological properties demonstrated by natural and synthetic derivatives. As a consequence there has been
Roberta L. da Costa, Douglas A. F. da Silva, Nanci C. de Lucas, Simon J. Garden   +3 more
doaj   +1 more source

Formal Synthesis of the Akuammiline Alkaloid (±)‐Strictamine via a (4 + 2) Annulation Reaction With a Donor–Acceptor Cyclobutane

Helvetica Chimica Acta, EarlyView.
We report a concise formal synthesis of (±)‐strictamine via a silylium‐catalyzed (4 + 2) annulation of a donor–acceptor cyclobutane, achieved in 13 steps from tryptamine. ABSTRACT The akuammiline alkaloids are complex monoterpene indole natural products with a rigid cage‐like architecture and diverse biological activities.
Clément Tanguy, Emma G. L. Robert, Jerome Waser   +2 more
wiley   +1 more source

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +2 more sources

Intramolecular direct arylation

, 2017
The research conducted for this thesis has led to the development of an intramolecular gold-catalysed direct arylation protocol whereby tethered arenes and aryltrimethylsilanes are coupled (Scheme 1). In Chapter 1, the key synthetic and mechanistic studies that have ultimately led to the conception of this project are introduced.
openaire   +2 more sources

2,3‐Dichloro‐5,6‐Dicyano‐1,4‐Benzoquinone (DDQ)‐Mediated CC Bond Formation: Redox Strategies from Stoichiometric to Catalytic Systems

ChemistryOpen, EarlyView.
2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone serves as a versatile oxidant and redox catalyst for CC bond formation through hydride abstraction or single‐electron transfer. Stoichiometric and catalytic systems enable benzylic, allylic, and aromatic CH activation under mild, metal‐free conditions, providing sustainable routes to complex and bioactive ...
Dohoon Cha, Sun‐Joon Min
wiley   +1 more source