Results 81 to 90 of about 3,524,925 (247)
Meloxicam (MLX) is a class II BCS non-steroidal anti-inflammatory drug (NSAID) with low solubility and manufacturing challenges due to its needle-like crystal habit, which causes poor flowability and high elasticity.
Hestiary Ratih +4 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Nov 30 shut down the WTO : mass nonviolent direct action info [recto]
Alternate title: November 30 shut down the WTO. Affiliated web page url: www.agitprop.org/artandrevolution/wto. Cosponsors include: Global Exchange, Rainforest Action Network, Ruckus Society, Project Underground, National Lawyers Guild, CISPES, IWW ...
Direct Action Network (DAN)
core
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
WTO direct action convergence, Seattle, WA (nov. 20-28), registration application [recto]
Alternate title: DAN registration. Affiliated web page url: www.agitprop.org/artandrevolution/wto. Library has 2 copies. Also sent out as document 6 of 19 in a Direct Action Network (DAN) organizing packet; these documents are contained in a 9 X 12 ...
Direct Action Network (DAN)
core
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Direct Processing of Document Images in Compressed Domain
2014 Fourth IDRBT Doctoral Colloquium, December 11-12, 2014 Hyderabad ...
Mohammed Javed +2 more
openaire +2 more sources
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source

