Results 71 to 80 of about 15,752,675 (317)

Development of a high-fidelity digital twin using the discrete element method for a continuous direct compression process. Part 1. Calibration workflow.

International journal of pharmaceutics
In this work, a high-fidelity digital twin was developed to support the design and testing of control strategies for drug product manufacturing via direct compression. The high-fidelity digital twin platform was based on typical pharmaceutical equipment,
D. Jajcevic, J. Remmelgas, Peter Toson, Marko Matić, Theresa Hörmann-Kincses, M. Beretta, J. Rehrl, J. Poms, Thomas F. O'Connor, A. Koolivand, Geng Tian, Scott M. Krull, J. Khinast   +12 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Preparation and Evaluation of Oral Disintegrating Tablets of Ketoprofen by Dirct Compression

Iraqi Journal of Pharmaceutical Sciences, 2017
Ketoprofen is a non-steroidal anti-inflammatory (NSAID) drug with analgesic, anti-inflammatory, and antipyretic effects. It is widely used in the treatment of inflammation and pain associated with rheumatic disorders such as rheumatoid arthritis ...
Saddam J.Nasser, Laith H. Sameen, Mowafaq M.Ghareeb   +2 more
doaj   +3 more sources

Acid-hydrolyzed nanocrystalline starch excipients for direct-compression tableting: a systematic review [PDF]

Exploration of Drug Science
Background: Acid-hydrolyzed nanocrystalline starch has attracted interest as a sustainable pharmaceutical excipient because of its crystallinity, compactibility, and potential suitability for direct compression tableting.
Mudassir Farooq, Saleh Sheikh
doaj   +1 more source

A Compression-Directional Entropic Stress Method for Shock-Regularized Compressible Flow

We introduce the Compression-Directional Entropic Stress (CoDeS) method inspired by information geometric regularization. CoDeS replaces scalar multidimensional entropic pressure with a tensor stress aligned with the principal directions of compression.
Xu, Bonan, Wen, Chihyung, Guo, Peixu
openaire   +2 more sources

Metrics for Stereoscopic Image Compression [PDF]

, 2012
Metrics for automatically predicting the compression settings for stereoscopic images, to minimize file size, while still maintaining an acceptable level of image quality are investigated.
GORLEY, PAUL,WARD, Gorley, Paul Ward
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Theoretical solution for the relationship between strength parameters of direct shear test and triaxial test

Yantu gongcheng xuebao
This paper analyzes the variation law of the Mohr's stress circle for normally consolidated soils in direct shear tests and triaxial compression tests. By comparing and analyzing the stress paths during the shearing process of the two tests, it is found ...
CAI Jifeng 1, CAI Jian 1, HU Zhongxiong 2
doaj   +1 more source

DEVELOPMENT AND EVALUATION OF FAST DISSOLVING TABLETS OF GLIMEPIRIDE

Zagazig Journal of Pharmaceutical Sciences, 2011
The objective of the current study was to assess the feasibility of developing fast dissolving tablets of glimepiride for type-2 diabetic patients, by direct compression and sublimation techniques.
BANDAR AL-DHUBIAB
doaj   +1 more source

Effect of the type of disintegrant on the characteristics of orally disintegrating tablets manufactured using new ready-to-use excipients (Ludiflash ® or Parteck ® ) by direct compression method

, 2012
The challenge in orally disintegrating tablets (ODTs) production encompasses the compromise between instantaneous disintegration and sufficient physico-mechanical properties, therefore the aim of this study was to evaluate the influence of selected ...
Aleks, ra Amelian, K. Winnicka
semanticscholar   +1 more source