Results 81 to 90 of about 3,248,511 (314)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

ACCOUNTING TREATMENT OF DIRECT CONTRACT COSTS

open access: yesEuropean Journal of Accounting, Finance & Business, 2023
This article examines the content and application of the provisions of the National Accounting Standard quot;Construction Contracts,quot; the General Plan of Accounting Accounts, and other normative acts related to contractual cost accounting. The results presented mainly refer to issues related to direct contractual costs, such as the classification ...
openaire   +2 more sources

DIRECT SALES IN THE CONTEXT OF ROMANIA'S UE INTEGRATION [PDF]

open access: yes
More recently, direct sales business is stimulated by the difficult market conditions. While retailers hardly bear fixed costs such as rent, administrative costs and tend to raise prices, customers fall back to products offered by direct sale.
Gherman Cristina
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

PHARMACOECONOMIC EVALUATION OF INFLUENZA AND PNEUMOCOCCAL VACCINATION IN EMPLOYEES OF THE JOINT STOCK COMPANY "RUSSIAN RAILWAYS" (JSCO "RZD") ON INVESTMENT FOR THE EMPLOYER

open access: yesФармакоэкономика, 2016
Objectives: To determine the clinical and economical effectiveness of influenza and pneumococcal vaccination in working adults without occupational exposures on respiratory diseases from an employer’s perspective. Methods.
D. A. Zhukov
doaj   +1 more source

Access to Information, Transaction Costs and Marketing Choice of Rural Households between Middlemen and Direct Buyers in Bangladesh [PDF]

open access: yes
This paper assesses the impact of information cost and other transaction costs on rural producers' discrete choice between selling to middlemen and direct buyers, and continuous choice of selling intensity to middlemen and direct buyers.
Chowdhury, Shyamal K
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

THE ANALYSIS OF METHODOLOGIC CHARACTERISTICS OF RESEARCHES ON SOCIAL AND ECONOMIC BURDEN OF DISEASES IN RUSSIA IN THE FRAMES OF DEVELOPMENT OF STANDARD COST OF ILLNESS METHODOLOGY FOR THE HEALTH TECHNOLOGY ASSESSMENT

open access: yesФармакоэкономика, 2015
the concept of the relations between public health and national economy has appeared long time ago, but the development of quantitative methods started only in the middle of the XXth century.
V. I. Ignatyeva, M. V. Avxentyeva
doaj  

A study of the direct costs of anesthesiology and reanimatology in Clinical center Serbia [PDF]

open access: yesHospital Pharmacology, 2018
Introduction: Modern health care implies the continuous development of human resources and the application of pharmacoeconomic analyzes during the introduction of new methods of treatment in medicine.
Majstorović Branislava A.M.   +7 more
doaj  

Home - About - Disclaimer - Privacy