Results 191 to 200 of about 7,321,963 (311)

Native Mass Spectrometry Enables Direct Detection of Endogenous Protein Complexes from Crude Lysates of Cultured Human Cells. [PDF]

Mass Spectrom (Tokyo)
Tajiri M, Tateishi Y, Wang Q, Morinaga H, Miura H, Arita Y, Nishiguchi M, Okumura D, Konuma T, Akashi S.   +9 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Rapid and Direct Detection of Methamphetamine in Biofluids using a MXene-Enabled Electrochemical Sensor. [PDF]

Adv Sci (Weinh)
Wang R, Deng X, Chen B, Shen J, Xu W, Zhu Y, Zhang Y, Yang H.   +7 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Redundant Residue Number System Assisted Multicarrier Direct-Sequence Code-Division Dynamic Multiple-Access for Cognitive Radios

A redundant residue number system assisted multicarrier direct-sequence code-division dynamic multiple-access (RRNS MC/DS-CDDMA) scheme is proposed for application in cognitive radios (CRs).
Zhang, Shuo, Yang, Lie-Liang, Zhang, Youguang   +2 more
core   +1 more source

Direct Detection of Viruses Using Antibody-Modified Gold Nanorods. [PDF]

J Biophotonics
Rodriguez A, Purvinsh Y, Holman AP, Kurouski D.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EV-Finder: Direct Detection of Extracellular Vesicle-Associated Proteins by Proximity Extension Assay for Multi-Cancer Screening. [PDF]

Int J Mol Sci
Tamai Y, Chiwaki F, Shiotani Y, Park HE, Jung EJ, Shin MG, Lee YE, Yoshioka Y, Ochiya T, Yoon TR.   +9 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Microfluidic toolbox using padlock probes and rolling circle amplification for direct detection and genotyping of viral RNA. [PDF]

RSC Adv
Varela JC, Gomes da Silva P, Lee H, Mesquita JR, Russom A, Soares RRG, Nilsson M.   +6 more
europepmc   +1 more source