Results 201 to 210 of about 1,605,931 (317)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Time- and Frequency-Domain-Spread Generalized Multicarrier DS-CDMA Using Subspace-Based Blind and Group-Blind Space–Time Multiuser Detection

open access: yes, 2008
—Subspace-based blind and group-blind space–time (ST) multiuser detection (MUD) is invoked for a smart-antenna-aided gen-eralized multicarrier direct-sequence code-division multiple-access (MC DS-CDMA) system communicating over a dispersive ST Rayleigh ...
Lie-liang Yang   +5 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Genetic-Algorithm-Assisted Multiuser Detection in Asynchronous CDMA Communications

open access: yes, 2004
—In an asynchronous direct-sequence code-division multiple-access, a specific bit of the reference user is interfered by two asynchronously arriving surrounding bits of all the other users supported by the system.
YEN, K., HANZO, L.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Direct Detection of Volatile Organic Compounds through Cationization Using ICP-MS/MS. [PDF]

open access: yesMass Spectrom (Tokyo)
Hirata T   +3 more
europepmc   +1 more source

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