Results 151 to 160 of about 9,105,244 (296)

17β-estradiol does not have a direct effect on the function of striatal cholinergic interneurons in adult mice in vitro. [PDF]

open access: yesFront Endocrinol (Lausanne), 2022
Kövesdi E   +8 more
europepmc   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

A comparison of different methods for decomposition of changes in expectation of life at birth and differentials in life expectancy at birth

open access: yesDemographic Research, 2005
Several methods were proposed to decompose the difference between two life expectancies at birth into the contribution by different age groups. In this study an attempt has been made to compare different methods with that of Chandra Sekar (1949) method ...
P. K. Murthy
doaj  

Bacillus vallismortis TU-Orga21 blocks rice blast through both direct effect and stimulation of plant defense. [PDF]

open access: yesFront Plant Sci, 2023
Thepbandit W   +4 more
europepmc   +1 more source

direct ecological effect

open access: yes
Citation: 'direct ecological effect' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14589 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The effectiveness of red-light therapy on myopia control depends on its direct effect: a mediation analysis. [PDF]

open access: yesJ Transl Med
Chen Q   +10 more
europepmc   +1 more source

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