17β-estradiol does not have a direct effect on the function of striatal cholinergic interneurons in adult mice in vitro. [PDF]
Kövesdi E +8 more
europepmc +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Several methods were proposed to decompose the difference between two life expectancies at birth into the contribution by different age groups. In this study an attempt has been made to compare different methods with that of Chandra Sekar (1949) method ...
P. K. Murthy
doaj
Bacillus vallismortis TU-Orga21 blocks rice blast through both direct effect and stimulation of plant defense. [PDF]
Thepbandit W +4 more
europepmc +1 more source
Citation: 'direct ecological effect' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14589 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The direct effect of drinking to cope on alcohol problems is not mediated by alcohol consumption: Invariance across gender and countries. [PDF]
Shuai R +4 more
europepmc +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The effectiveness of red-light therapy on myopia control depends on its direct effect: a mediation analysis. [PDF]
Chen Q +10 more
europepmc +1 more source
Direct effect of lipopolysaccharide and histamine on permeability of the rumen epithelium of steers ex vivo. [PDF]
Gao S +7 more
europepmc +1 more source

