Beyond weight loss: Disentangling the direct effects of semaglutide vs equivalent calorie restriction on reproductive systems of male and female rats. [PDF]
Sotzen MR +8 more
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The Direct Effect of Community Directives The Effect of the Unilever Judgment
openaire +2 more sources
RELMα establishes a permissive environment for influenza virus infection through direct effects on lung epithelial cells. [PDF]
Shirazi R +9 more
europepmc +1 more source
Tebufenozide has limited direct effects on simulated aquatic communities. [PDF]
Edge C +4 more
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Direct Effects of Polyploidization on Floral Scent. [PDF]
Schlager E +4 more
europepmc +1 more source
Direct Effects of Toxic Divalent Cations on Contractile Proteins with Implications for the Heart: Unraveling Mechanisms of Dysfunction. [PDF]
Gerzen OP +4 more
europepmc +1 more source
DAN budget proposal : master budget, 10/31/99 [recto]
Alternate title: D.A.N. budget proposal Alternate title: DAN budget ver 2.xls One of four documents stapled together: (1) "DAN budget proposal," (2) "Budget process proposal ; structure of action/organizing," (3) "Organizing task areas," (4) "Proposed ...
Direct Action Network (DAN)
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

