Results 171 to 180 of about 14,900,976 (311)

Beyond weight loss: Disentangling the direct effects of semaglutide vs equivalent calorie restriction on reproductive systems of male and female rats. [PDF]

open access: yesMol Metab
Sotzen MR   +8 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

RELMα establishes a permissive environment for influenza virus infection through direct effects on lung epithelial cells. [PDF]

open access: yesJ Virol
Shirazi R   +9 more
europepmc   +1 more source

Tebufenozide has limited direct effects on simulated aquatic communities. [PDF]

open access: yesEcotoxicology, 2022
Edge C   +4 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Direct Effects of Polyploidization on Floral Scent. [PDF]

open access: yesJ Chem Ecol
Schlager E   +4 more
europepmc   +1 more source

DAN budget proposal : master budget, 10/31/99 [recto]

open access: yes, 1999
Alternate title: D.A.N. budget proposal Alternate title: DAN budget ver 2.xls One of four documents stapled together: (1) "DAN budget proposal," (2) "Budget process proposal ; structure of action/organizing," (3) "Organizing task areas," (4) "Proposed ...
Direct Action Network (DAN)
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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