Results 191 to 200 of about 14,900,976 (311)

Direct Effects of Clinically Relevant Antibiotics on Mitochondrial Respiration. [PDF]

Int J Mol Sci
Sailer J, Schmitt S, Zischka H, Gnaiger E.   +3 more
europepmc   +1 more source

COVID-19 pandemic: Direct effects on the medical education in Pakistan. [PDF]

Ann Med Surg (Lond), 2022
Siddiqi H, Tahir MJ, Ullah I, Nazir A, Douba Z, Asghar MS, Yousaf Z.   +6 more
europepmc   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The changing cost-effectiveness of primary HIV prevention: simple calculations of direct effects. [PDF]

J Int AIDS Soc
Garnett GP, Herbeck JT, Akullian A.
europepmc   +1 more source

Elucidating the direct effects of the novel HDAC inhibitor bocodepsin (OKI-179) on T cells to rationally design regimens for combining with immunotherapy. [PDF]

Front Immunol, 2023
Holay N, Somma A, Duchow M, Soleimani M, Capasso A, Kottapalli S, Rios J, Giri U, Diamond J, Schreiber A, Piscopio AD, Van Den Berg C, Eckhardt SG, Triplett TA.   +13 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

An Approach for Studying the Direct Effects of Shock Waves on Neuronal Cell Structure and Function. [PDF]

Cells
Hanna M, Pfister BJ.
europepmc   +1 more source

Direct Effects of Vitamin D Supplementation on Ultramarathon-Induced Changes in Kynurenine Metabolism. [PDF]

Nutrients, 2022
Mieszkowski J, Brzezińska P, Stankiewicz B, Kochanowicz A, Niespodziński B, Reczkowicz J, Waldziński T, Kacprzak B, Siuba-Jarosz N, Petr M, Antosiewicz J.   +10 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets. [PDF]

Diabetes, 2022
Ben Nasr M, D'Addio F, Montefusco L, Usuelli V, Loretelli C, Rossi A, Pastore I, Abdelsalam A, Maestroni A, Dell'Acqua M, Ippolito E, Assi E, Seelam AJ, Fiorina RM, Chebat E, Morpurgo P, Lunati ME, Bolla AM, Abdi R, Bonventre JV, Rusconi S, Riva A, Corradi D, Santus P, Clark P, Nebuloni M, Baldi G, Finzi G, Folli F, Zuccotti GV, Galli M, Herold KC, Fiorina P.   +32 more
europepmc   +1 more source