Results 71 to 80 of about 176,367 (302)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Influence of Ultrasonic Irradiation of a 316L Weld Pool Produced by DED on the Mechanical Properties of the Produced Component

open access: yesCrystals
Additive manufacturing of metallic components often results in the formation of columnar grain structures aligned along the build direction. These elongated grains can introduce anisotropy, negatively impacting the mechanical properties of the components.
Dennis Lehnert   +7 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

DIRECT ION-BEAM DEPOSITION OF CARBON-FILMS ON SILICON IN THE ION ENERGY-RANGE OF 15-500 EV [PDF]

open access: yes, 1991
Direct ion beam deposition of carbon films on silicon in the ion energy range of 15-500 eV and temperature range of 25-800-degrees-C has been studied. The work was carried out using mass-separated C+ and CH3+ ions under ultrahigh vacuum. The films were
FENG X   +8 more
core  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Hybrid approaches for reducing defects in laser-based direct energy deposition of nickel-based superalloys [PDF]

open access: yes
Due to their outstanding high temperature properties, nickel-based superalloys are among the key materials in the energy and aerospace sector. With increasing importance of the additive manufacturing technology, direct energy deposition (DED) for ...
Heckert, M.   +6 more
core  

Diamond nucleation enhancement by direct low-energy ion-beam deposition [PDF]

open access: yes, 2000
Direct ion beam deposition was successfully applied for the nucleation of nanodiamond crystallites on mirror-polished Si(001) substrates. Low-energy (80-200 eV) argon, hydrocarbon, and hydrogen ions from a Kaufman ion source were used.
Peng, H.   +6 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Influence analysis of the layer orientation on mechanical and metallurgic characteristics of DED manufactured parts [PDF]

open access: yes, 2021
With an increasing trend in product individualization, manufacturing custom-designed solutions and focusing on the explicit industry’s needs are crucial to the manufacturer’s success.
Dambietz, Florian   +4 more
core  

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