Results 61 to 70 of about 593,417 (298)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Effect of auxiliary wire feeding on cold metal transfer directed energy deposition of stainless steel: A study on droplet transfer, formation characteristics, and microstructure

open access: yesJournal of Materials Research and Technology
While traditional cold metal transfer direct energy deposition (T-CMT-DED) can be sped up by increasing the deposition current; this often negatively affects the deposited part's shape and microstructure due to increased heat input.
Yi Feng, Qiming Jiang, Ding Fan
doaj   +1 more source

Direct Laser Interference Ink Printing Using Copper Metal–Organic Decomposition Ink for Nanofabrication

open access: yesNanomaterials, 2022
In this study, we developed an effective and rapid process for nanoscale ink printing, direct laser interference ink printing (DLIIP), which involves the photothermal reaction of a copper-based metal–organic decomposition ink. A periodically lined copper
Jun-Han Park   +5 more
doaj   +1 more source

The Origin of Large-scale HI structures in the Magellanic Bridge

open access: yes, 2007
We investigate the formation of a number of key large-scale HI features in the ISM of the Magellanic Bridge using dissipationless numerical simulation techniques. This study comprises the first direct comparison between detailed HI maps of the Bridge and
Bekki, K., Muller, E.
core   +1 more source

The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]

open access: yes, 2019
Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir   +5 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Linear support structures made of glass using additive manufacturing

open access: yesDiscover Mechanical Engineering
The increasing demand for large-scale, lightweight, and aesthetically customizable glass facades in modern architecture requires new approaches to enhance the mechanical performance of the used glass elements.
Franz Hesse   +3 more
doaj   +1 more source

Influence of Tungsten Addition on Microstructure and Tensile Properties of Ti6Al4V Fabricated by Laser-Directed Energy Deposition

open access: yesMetals, 2023
The addition of tungsten can improve the high-temperature oxidation resistance of titanium alloys. However, as its applications continue to expand, new demands are being placed on its room temperature strength.
Junguo Li   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Effect of Direct Energy Deposition Process Parameters on Single-Track Deposits of Alloy 718

open access: yesMetals, 2020
The effect of three important process parameters, namely laser power, scanning speed and laser stand-off distance on the deposit geometry, microstructure and segregation characteristics in direct energy deposited alloy 718 specimens has been studied ...
Suhas Sreekanth   +4 more
doaj   +1 more source

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