Results 51 to 60 of about 175,165 (302)

Biocompatible Direct Deposition of Functionalized Nanoparticles using Shrinking Surface Plasmonic Bubble

, 2020
Functionalized nanoparticles (NPs) are the foundation of diverse applications, such as photonics, composites, energy conversion, and especially biosensors.
Qiushi, Zhang, Tengfei, Luo, Hsueh-Chia, Chang, Satyajyoti, Senapati, Seunghyun, Moon, Eungkyu, Lee, Dezhao, Huang   +6 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Linear support structures made of glass using additive manufacturing

Discover Mechanical Engineering
The increasing demand for large-scale, lightweight, and aesthetically customizable glass facades in modern architecture requires new approaches to enhance the mechanical performance of the used glass elements.
Franz Hesse, Andreas Herrmann, Jörg Hildebrand, Jean Pierre Bergmann   +3 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Effect of auxiliary wire feeding on cold metal transfer directed energy deposition of stainless steel: A study on droplet transfer, formation characteristics, and microstructure

Journal of Materials Research and Technology
While traditional cold metal transfer direct energy deposition (T-CMT-DED) can be sped up by increasing the deposition current; this often negatively affects the deposited part's shape and microstructure due to increased heat input.
Yi Feng, Qiming Jiang, Ding Fan
doaj   +1 more source

Direct Laser Interference Ink Printing Using Copper Metal–Organic Decomposition Ink for Nanofabrication

Nanomaterials, 2022
In this study, we developed an effective and rapid process for nanoscale ink printing, direct laser interference ink printing (DLIIP), which involves the photothermal reaction of a copper-based metal–organic decomposition ink. A periodically lined copper
Jun-Han Park, Jung-Woon Lee, Yong-Won Ma, Bo-Seok Kang, Sung-Moo Hong, Bo-Sung Shin   +5 more
doaj   +1 more source

Partitioning of laser energy during directed energy deposition

Additive Manufacturing, 2017
Abstract An energy balance that describes the transfer of energy is proposed for the laser-based directed energy deposition process. The partitioning of laser energy was experimentally measured and accurately validated using a special process calorimeter for Ti-6Al-4V and Inconel 625™ alloys. The total energy provided by the laser was partitioned as:
Frederick Lia, Joshua Park, Jay Tressler, Richard Martukanitz   +3 more
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effect of Direct Energy Deposition Process Parameters on Single-Track Deposits of Alloy 718

Metals, 2020
The effect of three important process parameters, namely laser power, scanning speed and laser stand-off distance on the deposit geometry, microstructure and segregation characteristics in direct energy deposited alloy 718 specimens has been studied ...
Suhas Sreekanth, Ehsan Ghassemali, Kjell Hurtig, Shrikant Joshi, Joel Andersson   +4 more
doaj   +1 more source