Results 241 to 250 of about 290,974 (294)

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

Advanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae, Seungyong Shin, Joo Dong Park, Eun‐Young Koh, Seunghyo Ko, Jieun Han, Chun Gown Park, Dong‐Hyun Kim, Kun Na, Wooram Park   +9 more
wiley   +1 more source

Successful treatment of amoxicillin-induced linear IgA bullous dermatosis of childhood with rituximab: A case report and review of the literature

JAAD Case Reports
Tiffany Liu, BS, Emily Keyes, MD, Alreem Al-Nabti, MD, Nina Blank, MD, Cynthia Magro, MD   +4 more
doaj   +1 more source

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Practical Direct Immunofluorescence

The American Journal of Dermatopathology, 2020
Abstract: Direct immunofluorescence (DIF) remains a valuable tool that may be underused because of perceived challenges in the interpretation, limitations, and processing of DIF specimens. The aim of this review is to provide a practical guide for appropriately incorporating DIF in a variety of clinical diseases, such as autoimmune blistering
Randie H, Kim, Nooshin K, Brinster
openaire   +2 more sources

Granuloma annulare: direct immunofluorescence study

British Journal of Dermatology, 1976
Direct immunofluorescence studies were carried out in eleven specimens of granuloma annulare. The results (in all cases) indicate the presence of focal deposition of fibrin, localized primarily in the intervascular portion of the dermis, corresponding to the granulomatous and necrobiotic areas. These findings implicate the cellular mechanism of delayed
P, Umbert, R K, Winkelmann
openaire   +2 more sources

Direct immunofluorescence in pyoderma gangrenosum

British Journal of Dermatology, 1983
Direct immunofluorescence was done in fifty-one cases of pyoderma gangrenosum. Biopsy specimens were taken from the peripheral erythematous zone of the lesion. In thirty-one cases (61%), there was positive immunofluorescence, with perivascular deposition of immune reactants being the most frequent pattern (twenty-seven cases).
F C, Powell, A L, Schroeter, H O, Perry, W P, Su   +3 more
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Optimizing Direct Immunofluorescence

2014
Immunofluorescence is a laboratory technique that utilizes a fluorophore-labeled antibody to detect immune complexes in tissue. Most of the labeled antibodies used in a clinical laboratory bind the conserved domains within each class of human antibodies, allowing them to detect a wide range of autoimmune complexes.
Ian D, Odell, Deborah, Cook
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Candidiasis visualised by proteinase-directed immunofluorescence

Virchows Archiv A Pathological Anatomy and Histopathology, 1991
The secretory aspartic proteinases of Candida albicans and C. tropicalis are potential factors for virulence produced during infection. By indirect immunofluorescence, we have demonstrated proteinase antigen on elements of both species in deparaffinized tissue sections derived from clinical cases of mucosal and deep-seated candidiasis. Occasionally, we
R, Rüchel, F, Zimmermann, B, Böning-Stutzer, U, Helmchen   +3 more
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Direct Immunofluorescence in Sural Nerve Biopsies

European Neurology, 1988
Direct immunofluorescence (DIF) has been carried out in 66 sural nerve biopsies using antibodies against human IgG, IgA, IgM, C3, C4, albumin, fibrinogen, and kappa- and lambda-chains. In 37 out of 63 (59%) different neuropathies immunoglobulins or other plasma proteins were found within the peripheral nerves. IgM along the myelin sheaths were found in
SCHENONE, ANGELO, DE MARTINI, ISABELLA, TABATON, MASSIMO, P. Romagnoli, A. S. Akkad, D. Bianchini, MANCARDI, GIOVANNI LUIGI   +6 more
openaire   +3 more sources

Direct Immunofluorescence Diagnosis of Pemphigus without Biopsy

Journal of Cutaneous Medicine and Surgery, 1998
Background: Direct immunofluorescence (DIF) is a necessary examination tool for the diagnosis of pemphigus. The suction-blister-method splits the skin at the lamina lucida and it is possible with a scalpel to separate the entire epidermis from the dermis.
Feliciani, C., Mohammad Pour, S., Toto, P., Coscione, G., Amerio, P., Amerio, P.   +5 more
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Cytoid bodies in cutaneous direct immunofluorescence examination

Journal of Cutaneous Pathology, 2007
Background:  The clinical significance of scattered or grouped cytoid bodies seen on direct immunofluorescence (DIF) examination has not been systematically analyzed in a variety of disorders.Methods:  We prospectively studied skin biopsy specimens obtained from July 2002 to December 2005 for which DIF examination using immunoglobulin (Ig) A, IgG, IgM,
Yu-Hung, Wu, Yang-Chih, Lin
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