Results 51 to 60 of about 4,482,608 (231)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Design and Characterization of a Low-Current Compact Extraction and Matching System for a High-Frequency RFQ in Medical Applications

Instruments
A low-current compact extraction and matching system has been designed and experimentally tested to evaluate its capability for direct proton injection of 15 keV into a 750 MHz radiofrequency quadrupole for medical applications.
Aristeidis Mamaras, Francesco Di Lorenzo, Alessandra Lombardi, Eleonora Pasino, Dimitrios Sampsonidis   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Parametric Investigation of Methanol Spray Combustion Under Direct-Injection Conditions

Fluids
This study presents a systematic mapping of methanol spray autoignition, lift-off, and flame development across an engine-relevant range of ambient temperatures (1000–1200 K), injection pressures (70–130 MPa), and O2 concentrations (21–15 vol.%), using a
Kirtan Aryal, Guanxiong Zhai, Ruiyuan Cao, Yijun Lin, Shijie Xu, Kar Mun Pang, Cheng Wang, Guan Heng Yeoh, Qing Nian Chan   +8 more
doaj   +1 more source

Combustion Modeling for Modern Direct Injection Diesel Engines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2012
In order to comply with stringent pollutant emissions regulations, a detailed analysis of the engine combustion and emission is required. In this field, computational tools like CFD and engine cycle simulation play a fundamental role. Therefore, the goal
Samad Jafarmadar, Alborz Zehni
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

One-Dimensional Thermodynamic Analysis of a Novel Two-Stroke Aircraft Diesel Engine with an Integrated Cylinder–Dual-Role Crankshaft Architecture [PDF]

INCAS Bulletin
This study presents the one-dimensional thermodynamic assessment of a novel two-stroke, direct-injection aircraft Diesel engine incorporating two original mechanical elements, a dedicated cylinder architecture, and a dual-role crankshaft.
Marius Costel OPREA, Daniel-Eugeniu CRUNTEANU   +1 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Water Injection Effects on the Performance and Emission Characteristics of a CI Engine Operating with Biodiesel [PDF]

, 2012
Biodiesel is one of the most promising renewable, alternative and environmentally friendly biofuels that can be used in diesel engine without any need for any modification in the engine.
Gu, Fengshou, Ball, Andrew, Ball, A. D., A.D. Ball, Gu, F., F. Gu, Mishra, R., Tesfa, Belachew, Tesfa, B., Mishra, Rakesh, B. Tesfa, R. Mishra   +11 more
core   +1 more source