Results 71 to 80 of about 4,482,608 (231)

Quantitative Analysis of Microcystin-LR in Drinking Water Comparing On-Line Solid Phase Extraction and Direct Injection LC/MS/MS

ASEAN Journal on Science and Technology for Development, 2018
An efficienmethod for microcystin-LRin drinking water at the sub-ng/l level applying on-line solid phase extraction (SPE) with LC/MS/MS detection and comparing it to direct injection LC/MS/MS is presented.
R. MALARVILI, Y.Y. LOW, A. ZAITON
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Research on the Impact of Blending Dissociated Methanol Gas on the Performance and Emissions of Marine Medium-Speed Methanol Engines

Journal of Marine Science and Engineering
This study conducts a detailed analysis of the mixed combustion of dissociated methanol gas (DMG) and methanol in a marine medium-speed methanol engine through numerical simulation methods.
Xiaoyu Liu, Jie Zhu, Zhongcheng Wang, Zihan Wang, Zihao Zhao, Wenhua Wang, Haiping Cai   +6 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Performance Enhancement of Internal Combustion Engines through Vibration Control: State of the Art and Challenges

Applied Sciences, 2019
Internal combustion engines (ICEs) are the primary source of power generation in today’s driving vehicles. They convert the chemical energy of the fuel into the mechanical energy which is used to drive the vehicle.
Hojat Mahdisoozani, Mehrdad Mohsenizadeh, Mehdi Bahiraei, Alibakhsh Kasaeian, Armin Daneshvar, Marjan Goodarzi, Mohammad Reza Safaei   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

CFD Analysis of Diesel Pilot Injection for Dual-Fuel Diesel–Hydrogen Engines

Energies
In the pursuit of cleaner and more efficient internal combustion engines, dual-fuel strategies combining diesel and hydrogen are gaining increasing attention.
Gianluca D’Errico, Giovanni Gaetano Gianetti, Tommaso Lucchini, Alastar Gordon Heaton, Sanghoon Kook   +4 more
doaj   +1 more source

Effects of Direct Fuel Injection Strategies on Cycle-by-Cycle Variability in a Gasoline Homogeneous Charge Compression Ignition Engine: Sample Entropy Analysis

Entropy, 2015
In this study we summarize and analyze experimental observations of cyclic variability in homogeneous charge compression ignition (HCCI) combustion in a single-cylinder gasoline engine.
Jacek Hunicz, Alejandro Medina, Grzegorz Litak, Pedro L. Curto-Risso, Lev Guzmán-Vargas   +4 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source