Results 81 to 90 of about 4,482,608 (231)

Optimization of CO₂ Flooding Strategies for an Undeveloped Chang 8 Tight Oil Reservoir in the Ordos Basin, China

Energies
The Chang 8 tight oil reservoir in the Xifeng area of the Ordos Basin is characterized by poor reservoir properties, making conventional water flooding ineffective for efficient reservoir development.
Jiwei Wang, Peihao Xu, Long Liu, Yongjian Feng, Qiang Liu, Qinglong Zhu, Luming Shi, Wei Wang   +7 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A 68dB-SNDR, 100-Frame/s CMOS Analog Front-End for a SWIR Detector

Eng
For the application of a high-performance shortwave infrared (SWIR) detector, a fully integrated analog front-end (AFE) circuit is proposed in this paper, which includes a readout integrated circuit (ROIC) and a 12-bit/100 kHz two-step single-slope ...
Jiming Chen, Zhifeng Chen, Yuyan Zhang, Qiaoying Gan, Weiyi Zheng, Caiping Zheng, Sixian Li, Ying Gao, Chengying Chen   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Experimental comparison of different injection timings in an HCCI engine fueled with n-heptane

International Journal of Automotive Science and Technology, 2017
One of the most effective methods to control the combustion phasing of a homogeneous charged compression ignition (HCCI) engine is injection timing. Injection timing affects the homogeneity of the mixture, start of combustion and heat release rate.
Mahdi Shahbakhthi̇, Hamit Solmaz, Ahmet Uyumaz, Kaushik Kannan, H. Serdar Yücesu, Seyfi Polat   +5 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Direct injection ultra-performance liquid chromatography–tandem mass spectrometry for the high-throughput determination of etomidate and etomidate acid in wastewater

Journal of Water and Health
Etomidate (ET), a hypnotic agent used for the induction of anesthesia, is rapidly metabolized to etomidate acid (ETA) in the liver. Recently, ET has become one of the most serious alternative drugs of abuse in China.
Shuai Yuan, Yue Xiao, Ruxin Luo, Xin Wang, Ping Xiang   +4 more
doaj   +1 more source