Results 21 to 30 of about 175,047,704 (220)
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu +8 more
wiley +1 more source
Evaluation of the front-fixing method capabilities for numerical modelling of diffusion in moving systems [PDF]
Application of a finite difference front fixing method to various problems with moving boundaries and nonlinear material properties is discussed. Advantages and implementation problems of the method are highlighted.
Sykulski, J. K. +3 more
core +2 more sources
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Liouville type theorems involving fractional order systems
In this paper, let α be any real number between 0 and 2, we study the following semi-linear elliptic system involving the fractional Laplacian: (−Δ)α/2u(x)=f(u(x),v(x)),x∈Rn,(−Δ)α/2v(x)=g(u(x),v(x)),x∈Rn. $\begin{cases}{\left(-{\Delta}\right)}^{\alpha /2}
Liao Qiuping, Liu Zhao, Wang Xinyue
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Numerical investigation of the direct tensile behaviour of laminated and transversely isotropic rocks containing incipient bedding planes with different strengths [PDF]
\ua9 2017 Elsevier Ltd. The anisotropic direct tensile behaviour of laminated and transversely isotropic Midgley Grit sandstone (MGS) was investigated in this paper using a particle-based discrete element method (DEM) with consideration of the incipiency
Duan K +4 more
core +2 more sources

