Results 31 to 40 of about 175,047,704 (220)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Some Properties of Positive Solutions for Nonlinear Systems Involving Pseudo-Relativistic Operators
Fractal and FractionalIn this paper, we mainly investigate the radial symmetry and monotonicity of positive solutions for a nonlinear system involving pseudo-relativistic operators and fractional derivatives of order (0,1).
Xiaoshan Wang, Zengbao Wu
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Implicitization using moving planes and moving quadrics
, 2017 In this talk, I will first review some recent work on constructing moving quadrics from moving planes that follow a tensor product surface with no base points, assuming that there are no moving planes of low degree following the surface.
Chen, Falai
core +1 more source
The properties of a new fractional g-Laplacian Monge-Ampère operator and its applications
Advances in Nonlinear AnalysisIn this article, we first introduce a new fractional gg-Laplacian Monge-Ampère operator: Fgsv(x)≔infP.V.∫Rngv(z)−v(x)∣C−1(z−x)∣sdz∣C−1(z−x)∣n+s∣C∈C,{F}_{g}^{s}v\left(x):= \inf \left\{\hspace{0.1em}\text{P.V.}\hspace{0.1em}\mathop{\int }\limits_{{{\mathbb{
Wang Guotao, Yang Rui, Zhang Lihong
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Moving Force Identification based on the Frequency-Time Domain Method
, 2003 This paper addresses the problem on the identification of moving vehicle axle loads based on measured bridge responses using a frequency-time domain method.
Chan, Tommy H.T., Yu, Ling
core +1 more source
A Moving IRBFN-Based Galerkin Meshless Method [PDF]
, 2010 A novel meshless method based on Radial Basis Function networks (RBFN) and variational principle (global weak form) is presented in this paper. In this method, the global integrated RBFN is localized and coupled with the moving least square method via ...
Le, Phong B. H. +7 more
core +1 more source
Moving planes and moving spheres following dupin cyclides
, 2017 We provide explicit representations of three moving planes that form a $\mu$-basis for a cyclide in standard position and pose. We also show how to compute \(\mu\)-bases for cyclides in general position and pose from their implicit equations. The role of
Jia, Xiaohong
core +1 more source