Results 51 to 60 of about 241,674 (210)

Ray-tracing through the Millennium Simulation: Born corrections and lens-lens coupling in cosmic shear and galaxy-galaxy lensing

, 2009
(abridged) We study the accuracy of various approximations to cosmic shear and weak galaxy-galaxy lensing and investigate effects of Born corrections and lens-lens coupling. We use ray-tracing through the Millennium Simulation to calculate various cosmic-
Amendola, Aubert, Bacon, Bartelmann, Bartelmann, Benjamin, Blandford, Bower, Carbone, Cooley, Cooray, Cooray, Couchman, Crittenden, Croton, Das, De Lucia, Eisenstein, Faure, Fosalba, Frigo, Fu, Gavazzi, Hamana, Heymans, Hilbert, Hilbert, Hilbert, Hirata, Hoekstra, J. Hartlap, Jain, Jain, Mandelbaum, Massey, Massey, Massey, Meneghetti, Munshi, Neto, P. Schneider, Pace, Peacock, Peirani, Rozo, S. D. M. White, S. Hilbert, Schimd, Schneider, Schneider, Seitz, Seitz, Seljak, Semboloni, Shapiro, Simon, Smith, Spergel, Springel, Springel, Taylor, Tinker, Vale, Van Waerbeke, Wambsganss, Wambsganss, Wambsganss, White, White, White, Ziour   +70 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Simulation of thermal processes in a half-space under heating by a moving source with a uniformly distributed heat flow

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук
Using the method of applying instantaneous point sources, a solution was obtained to the problem of heat conduction during surface heating of a body in the form of a half-space by a uniformly distributed highly concentrated heat flux moving at a constant
A. V. Verameichyk, B. G. Kholodar
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Tectonic Evolution of the Intra-plate Structures of Sarmatia in the Phanerozoic. 2. Tectonic frameworks of deformations

Вісник Харківського національного університету імені В.Н. Каразіна. Серія Геологія. Географія. Екологія
Objective. Based on data from the Dnieper-Donetsk Aulacogene, the role of different-age systems of crustal faults as tectonic frameworks of deformations of the Sarmatian plate was investigated. Methods.
Oleksii Bartaschuk, Vasyl Suyarko, Oleksandr Chuienko   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A semilinear Dirichlet problem involving the fractional Laplacian in R+ n

Advanced Nonlinear Studies
We investigate the Dirichelt problem involving the fractional Laplacian in the upper half-space R+n=x∈Rn∣x1>0 ${\mathbb{R}}_{+}^{n}=\left\{x\in {\mathbb{R}}^{n}\mid {x}_{1}{ >}0\right\}$ :  (−Δ)su(x)=f(u(x)),x∈R+n, u(x)>0,x∈R+n, u(x)=0,x∉R+n.
Li Yan
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source