Results 61 to 70 of about 16,342 (222)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Real-Time Stereo Visual Servoing of a 6-DOF Robot for Tracking and Grasping Moving Objects [PDF]
, 2013 Robotic systems have been increasingly employed in various industrial, urban, mili-tary and exploratory applications during last decades. To enhance the robot control per-formance, vision data are integrated into the robot control systems.
Mohebbi, Abolfazl
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Qualitative properties of solutions for system involving fractional Laplacian
, 2022 In this paper, we consider the following nonlinear system involving the fractional Laplacian \begin{equation} \left\{\begin{array}{ll} (-\Delta)^{s} u (x)= f(u,\,v), \\ (-\Delta)^{s} v (x)= g(u,\,v), \end{array} \right.
Zhuo, Ran, Lü, Yingshu
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FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Algorithms for trajectory integration in multiple views
, 2009 PhDThis thesis addresses the problem of deriving a coherent and accurate localization of moving objects from partial visual information when data are generated by cameras placed in di erent view angles with respect to the scene.
Kayumbi-Kabeya, Gabin-Wilfried
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Medição óptica, comparação e sinalização de superfícies com forma livre de grande extensão [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2010Muitas superfícies, como cascos de navio, "carenagens" de automóveis e aeronaves, assim como pás de ...
Pinto, Tiago Loureiro Figaro da Costa
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