Results 71 to 80 of about 21,516,320 (280)

Social-economic burden of Pompe disease with late onset in the Russian Federation

Качественная клиническая практика, 2019
Pompe disease (PD) — a rare disease with progressive muscles weakness, cardiac and pulmonary insufficiency and others vital life-threatening symptoms without enzyme replacement therapy (ERT).
A. S. Kolbin, I. A. Vilyum, Yu. E. Balikina, M. A. Proskurin, O. I. Karpov   +4 more
doaj   +1 more source

Examination of medical and non-medical direct costs of outpatients and hospitalized cancer patients in Shiraz, Iran

Payesh, 2015
Objective (s): With more than 12 million new cases of cancers and nearly 7.6 million deaths all around the world in 2007, cancer currently is the third leading cause of death in the world. This study was conducted to determine medical and non-medical direct costs of cancer patients’ hospitalized in Namazi Hospital in Shiraz, Iran.
Jamshid Bahmei, Hamed Rahimi, Abdal saleh Jafari, Mostafa Habibyan   +3 more
openaire   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Annual direct cost of dry eye in Japan

, 2012
Yoshinobu Mizuno, Masakazu Yamada, Chika ShigeyasuDivision for Vision Research, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, JapanOn behalf of The Dry Eye Survey Group, National Hospital Organization of JapanBackground ...
Shigeyasu C, Mizuno Y, Yamada M
core  

Total and average direct medical cost by disease category (USD) (Mean ± SD, medium).

, 2019
Total and average direct medical cost by disease category (USD) (Mean ± SD, medium).
Arthorn Riewpaiboon (3439406), A. Thi Win Shwe (6490502), Sitaporn Youngkong (6021329), Usa Chaikledkaew (4909543)   +3 more
core   +1 more source

Estimation of direct and indirect costs associated with obesity treatment interventions among adult populations in Iran

BMC Health Services Research
Background The prevalence of obesity worldwide has reached pandemic levels and is anticipated to escalate swiftly in developing nations. Given the substantial surge in obesity rates observed over the last three decades, assessing obesity-related costs is
Faezeh Valaei Sharif, Zahra Sharif, Nazila Yousefi, Somayeh Mokhber   +3 more
doaj   +1 more source

Medical and non-medical direct costs of cancers in patients hospitalized in Imam Khomeini cancer institution - 2010

بیمارستان, 2012
Background: With more than 12 million new cases of cancers and nearly 7.6 million deaths all around the world in 2007, cancer currently is the third leading cause of death in the world. This study was conducted to determine medical and non-medical direct costs of cancer patients’ hospitalized in the cancer institute affiliated with Imam Khomeini ...
M Bazyar, A pourreza, Iraj harirchi, F Akbari, M Mahmoudi   +4 more
openaire   +1 more source

Assessing Direct Non-Medical and Indirect Costs for Patients Migrating from Underserved to Developed Regions in Iran: A Study from 2020-2021

Journal of Health Sciences and Surveillance System
Background: Access to healthcare services is a prerequisite for societal justice. Unfair distribution of these services can lead to patient migration to cities with higher quality medical centers for better medical services. This study aimed to determine the direct and indirect non-medical costs of patients referred from Sistan and Balouchestan to ...
Khammarnia, Mohammad, Barfar, Eshagh, Abrishami, Hossein, Ramezani Siakhulak, Fariba   +3 more
openaire   +2 more sources