Results 191 to 200 of about 73,785 (303)

Choosing Wisely: Key Feature Examinations as a Powerful Approach to Foster Clinical Reasoning in Dental Education

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Clinical reasoning is considered a core skill for physicians, and its training should already be addressed in undergraduate medical education. At the University Medical Center Göttingen, students have been able to engage in formative key feature examinations since 2013.
Marc André Ackermann, Tim Becker, Nima Gholamzadeh Biji, Thomas Meyer, Sabine Sennhenn‐Kirchner   +4 more
wiley   +1 more source

Improving Safe Initiation of Direct Oral Anticoagulant Therapy: A Two-Cycle Quality Improvement Project. [PDF]

Cureus
Shrestha O, Joshi H, San S, Richards J.
europepmc   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Procoagulant off-target effect of the direct oral anticoagulant reversal agent Andexanet alfa. [PDF]

Blood Vessel Thromb Hemost
Hoornstra IMS, Zhao J, Middelveld H, Sun S, Schönichen C, Heemskerk JWM, Stragier H, Heylen R, de Laat B, Roest M.   +9 more
europepmc   +1 more source

Treatment With Valoctocogene Roxaparvovec in a Patient With Severe Hemophilia A Led to Sustained Normal FVIII Levels

Haemophilia, EarlyView.
ABSTRACT Introduction Valoctocogene roxaparvovec, an adeno‐associated virus (AAV)‐based gene therapy, enables endogenous factor VIII (FVIII) expression in patients with severe hemophilia A without the need for regular FVIII infusions. Long‐term follow‐up assesses durability, safety, and immune‐related challenges following gene therapy.
Kerstin Herbst, Behnaz Pezeshkpoor, Claudia Klein, Thilo Albert, Philipp Lutz, Christian Strassburg, Ulrich Spengler, Georg Goldmann, Johannes Oldenburg   +8 more
wiley   +1 more source

Discrepant Outcomes of Direct Oral Anticoagulant Trials in Device-Detected Atrial Fibrillation after Stroke: Insights from NOAH-AFNET 6 and ARTESIA. [PDF]

Clin Appl Thromb Hemost
Liu H, Li Z, Chen X, Zhou J.
europepmc   +1 more source

Fostamatinib treatment for patients with antiphospholipid syndrome and low platelet count: A case series

British Journal of Haematology, EarlyView.
Ekaterina Balaian, Rosa Sonja Alesci, Sandra Marten, Julia‐Annabell Georgi, Christiane Naue, Martin Bornhäuser, Karolin Trautmann‐Grill   +6 more
wiley   +1 more source

The Swiss Haemophilia Registry–Report From the First 8 Years

Haemophilia, EarlyView.
ABSTRACT Introduction Patient registries capture disease related information and provide a valuable source for real‐world data on rare diseases and their management. The Swiss Haemophilia Registry (SHR) was established in 2015 on the basis of a new Swiss federal human research act.
Alessandra Bosch, Lorenzo Alberio, Pierre Fontana, Lukas Graf, Johanna A. Kremer Hovinga, Nicolas von der Weid, Mattia Rizzi, Manuela Albisetti, the Swiss Haemophilia Network   +8 more
wiley   +1 more source

Direct oral anticoagulant-associated intracerebral hemorrhage: The challenge of the 21st century. [PDF]

Eur Stroke J
Seiffge D, Steiner T.
europepmc   +1 more source

Reference Values for Pulse Oximetry Testing in Permanent Teeth: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Pulse oximetry is an accurate diagnostic method for assessing the condition of the dental pulp; however, the normal oxygen saturation levels for each tooth type are yet to be clearly defined. Objectives This systematic review and meta‐analysis aims to answer the question: What are the reference values for pulse oximetry testing in ...
Lilian Tietz, Theodoro Weissheimer, Cassiano Kuchenbecker Rösing, Marcus Vinicius Reis Só   +3 more
wiley   +1 more source