Prescribing patterns and clinician preferences for direct oral anticoagulant use in unusual site venous thromboembolism: a cross-sectional analysis from the Direct oral anticoagulants in Unusual Site venous Thromboembolism (DUST) study. [PDF]
Riva N +24 more
europepmc +1 more source
ABSTRACT Borderline prolongation of routine clotting assays—particularly the activated partial thromboplastin time (aPTT)—is a common interpretative challenge in laboratory hematology. These reproducible but mildly prolonged results often lie just beyond the upper reference limit and can trigger unnecessary follow‐up, delays, or misinterpretation ...
Nikolaos Androulakis +3 more
wiley +1 more source
Direct Oral Anticoagulant Use in Older Adults with Atrial Fibrillation: Challenges and Solutions. [PDF]
Bhandari M +6 more
europepmc +1 more source
ABSTRACT Introduction Fully automated thrombin generation (TG) assays facilitate the transition from research to clinical application. We conducted a multicenter inter‐laboratory study using the ST Genesia analyzer to evaluate assay performance and establish reference intervals in healthy adults from Spain and Portugal.
Diego Velasco‐Rodríguez +21 more
wiley +1 more source
Real-world management and outcomes of venous thromboembolism in patients with cancer and limited life expectancy in the direct oral anticoagulant era: insights from the COMMAND VTE Registry-2. [PDF]
Kuno T +39 more
europepmc +1 more source
ABSTRACT Background While various pulsed field ablation (PFA) systems for atrial fibrillation (AF) ablation have become available in recent years, data comparing long‐term efficacy outcomes remain limited. Purpose To compare long‐term efficacy outcomes of two commercially available PFA systems to perform pulmonary vein isolation (PVI) for AF in a ...
Marisa van der Graaf +18 more
wiley +1 more source
Bleeding-Related Hospitalizations Among Direct Oral Anticoagulant Users and Nonusers in Medicare Fee-For-Service: Variation in Prevalence, Burden, and Characteristics. [PDF]
Bazell CM +7 more
europepmc +1 more source
A standardized, nurse‐led heparinization protocol significantly improves the speed, consistency, and precision of achieving therapeutic ACT levels during left atrial ablation, while reducing excessive anticoagulation and maintaining a comparable safety profile to conventional operator‐guided dosing.
Vanessa Sciacca +14 more
wiley +1 more source
Direct Oral Anticoagulant-Related Bleeding in Atrial Fibrillation Patients Leads to <i>ADAMTS7</i> Promoter Demethylation. [PDF]
Ragia G +8 more
europepmc +1 more source

