Results 51 to 60 of about 4,657,009 (154)

DOAC‐Stop in lupus anticoagulant testing: Direct oral anticoagulant interference removed in most samples

Research and Practice in Thrombosis and Haemostasis, 2021
Background The use of direct oral anticoagulants (DOACs) is a convenient therapeutic option for patients at risk of thrombosis. DOACs interfere with clot‐based testing for the identification of lupus anticoagulant antibodies (LACs) in patients with ...
Steven Andrew Baker, Jing Jin, Christopher Pfaffroth, Trang Vu, James L. Zehnder   +4 more
doaj   +1 more source

Direct Oral Anticoagulant Drugs in Dental Clinical Practice

, 2017
The direct oral anticoagulant drugs (DOAC) are generally safe and effective in several clinical settings including acute venous thromboembolic disease, prophylaxis in the postoperative setting, prevention of thromboembolism in patients with non-valvular ...
I. Malachovsky, K. Mikuskova, P. Gengelova, M. Kasaj, D. Statelova, J. Stasko, M. Janickova, M. Smatanova   +7 more
core   +2 more sources

Intravenous Thrombolysis in Patients on Direct Oral Anticoagulants: Analysis of the Get With The Guidelines Stroke Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Intravenous thrombolysis for acute ischemic stroke (AIS) is a proven effective treatment. Whether thrombolysis in patients with AIS with recent direct oral anticoagulant (DOAC) use is safe and efficacious is not well established.
Shadi Yaghi, Liqi Shu, Eva A. Mistry, Opeolu Adeoye, Lee Schwamm, Steven Messe, Mitchell S. V. Elkind, Malik Ghannam, Adam de Havenon, Karen Furie, Ying Xian, Christopher Streib, Runqi Wangqin, Nils Henninger, Jeffrey L. Saver, Eric E. Smith   +15 more
doaj   +1 more source

Trend of anticoagulant therapy in elderly patients with atrial fibrillation considering risks of cerebral infarction and bleeding

Scientific Reports, 2023
The introduction of direct oral anticoagulants (DOACs) has greatly changed the use of anticoagulant therapy in patients with non-valvular atrial fibrillation (Af).
Noriko Tsuji, Yoshimitsu Takahashi, Michi Sakai, Shosuke Ohtera, Junji Kaneyama, Kosai Cho, Genta Kato, Shigeru Ohtsuru, Takeo Nakayama   +8 more
doaj   +1 more source

Forest plot of overall survival for subgroup analyses using a multivariable Cox proportional hazards model that included the anticoagulant group, the subgroup covariate of interest, and the subgroup-by-treatment interaction.

, 2022
CI, confidence interval; DOAC, direct oral anticoagulant.
Donna Neuberg (24536), Rushad Patell (12635871), Jeffrey I. Zwicker (12635874), Thita Chiasakul (9991691), Robert Redd (9543354), Ellen P. McCarthy (11485967), Adeel M. Khan (12635868)   +6 more
core   +1 more source

Class of anticoagulant prescribed and aspirin use by CHA₂DS₂-VASc score^a.

, 2023
CHA2DS2-VASc, congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke or transient ischemic attack, vascular disease, age 65 to 74 years, sex category; DOAC, direct-acting oral anticoagulant; OAC, oral anticoagulant.
Carmine Colavecchia (16814264), Peter Brady (16814270), J. Rebecca Mills (7920743), Matthew Cato (12101718), Rasha Khatib (509417), Nicole Glowacki (16814261), Scott Glosner (16814267)   +6 more
core   +1 more source

Development and Validation of a Machine Learning Model to Predict Oral Anticoagulant Use in Stroke From Prothrombin Time–International Normalized Ratio and Activated Partial Thromboplastin Time

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Timely recognition of oral anticoagulant use is critical in acute stroke but is often hampered by impaired consciousness and unavailable medication history.
Gaku Fujiwara, Yoshinari Nagakane, Nobukuni Murakami, Eiichi Suehiro, Naoya Hashimoto, Sohei Yoshimura, Kazunori Toyoda, Yohei Okada   +7 more
doaj   +1 more source

Thrombotic events and rebleeding after hemorrhage in patients taking direct oral anticoagulants for non-valvular atrial fibrillation.

PLoS ONE, 2021
Several direct oral anticoagulants have been developed to prevent cardiogenic thrombosis in patients with atrial fibrillation, on the other hand, have the complication of bleeding.
Daisuke Yanagisawa, Koichiro Abe, Hirohito Amano, Shogo Komatsuda, Taku Honda, Daisuke Manabe, Hirosada Yamamoto, Ken Kozuma, Shinya Kodashima, Yoshinari Asaoka, Takatsugu Yamamoto, Atsushi Tanaka   +11 more
doaj   +1 more source

Direct oral anticoagulant (DOAC)-mediated vasodilation:Role of nitric oxide [PDF]

, 2019
Anticoagulant therapy is commonly prescribed for both the acute treatment, and long-term prevention of venous thromboembolism (VTE), and as primary and secondary prevention of stroke in the context of atrial fibrillation (AF) [1].
Mabley, Jon; id_orcid, Sayed, Abdelrahman, Arya, Roopen, Patel, Jignesh, Scutt, Greg   +4 more
core   +1 more source

Additional file 1 of Inappropriate direct oral anticoagulant dosing in atrial fibrillation patients is associated with prescriptions for outpatients rather than inpatients: a single-center retrospective cohort study

, 2020
Additional file1: Table S1. Comparison of demographic characteristics among the 4 groups, underdosing, appropriate reduced dosing, overdosing, and appropriate standard dosing of direct oral anticoagulants. Table S2.
Hidenori Urata (5802017), Masanobu Uchiyama (1466110), Yoshihiko Nakamura (405559), Keisuke Okamura (5802011), Kazuyuki Shirai (8439930), Shiro Jimi (8439921), Motoyasu Miyazaki (4926226), Kaoko Tokura (8439918), Sen Adachi (8439924), Tomohiko Yamamoto (8439927), Momoko Misaki (8439915), Yuya Sakamoto (5802005), Koichi Matsuo (270064), Osamu Imakyure (5802023)   +13 more
core   +1 more source