Results 91 to 100 of about 41,597 (297)
, 2013 We present the case of an aphasic 77-year-old stroke patient with left distal M1 occlusion who received rt-PA for thrombolysis while on oral anticoagulant treatment with dabigatran (150 mg b.i.d.).
Baas, Horst +7 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen +8 more
wiley +1 more source
Bleeding, Thrombosis and Vascular BiologyPatients with cancer have an increased risk of thrombosis requiring anticoagulation. Direct oral anticoagulants have become the primary anticoagulant of choice in most patients with cancer. Patients with cancer also receive many concomitant medications,
Tzu-Fei Wang +2 more
doaj +1 more source
New horizons in anticoagulation: Direct oral anticoagulants and their implications in oral surgery.
Medicina oral, patologia oral y cirugia bucal, 2017 Thrombotic disorders remain a leading cause of death in the Western World. For decades, vitamin K antagonists used in the prevention of this pathology, such as warfarin or sintrom, were the only oral agents available for long-term anticoagulation, in spite of their disadvantages.An electronic database search was carried out on MedLine and The Cochrane ...
Serrano-Sánchez,Víctor +7 more
openaire +3 more sources
British Journal of Clinical Pharmacology, EarlyView.Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi +3 more
wiley +1 more source
Open Heart, 2019 Purpose We sought to assess the safety of performing diagnostic radial access coronary angiography with uninterrupted anticoagulation on patients receiving direct oral anticoagulant therapy.Background Direct oral anticoagulants have become a popular ...
Napohn Chongprasertpon +6 more
doaj +1 more source
Evaluation of bleeding in patients receiving direct oral anticoagulants
, 2017 Erika L Hellenbart,1 Kathleen D Faulkenberg,2 Shannon W Finks3 1University of Illinois at Chicago College of Pharmacy, Chicago, IL, 2Cleveland Clinic, Cleveland, OH, 3University of Tennessee College of Pharmacy, Memphis, TN, USA Abstract: Direct oral ...
Faulkenberg KD, Hellenbart EL, Finks SW
core
Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients
British Journal of Clinical Pharmacology, EarlyView.Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen +14 more
wiley +1 more source
Direct oral anticoagulants in cirrhosis: Rationale and current evidence. [PDF]
Cirrhosis is a major health concern worldwide with a complex pathophysiology affecting various biological systems, including all aspects of haemostasis.
Bertaggia Calderara, Debora +21 more
core +1 more source
Applying machine learning to pharmacovigilance data: A proof‐of‐concept study
British Journal of Clinical Pharmacology, EarlyView.Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus +6 more
wiley +1 more source