Results 171 to 180 of about 41,597 (297)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Pharmacogenomics of direct oral anticoagulants: a systematic review and meta-analysis. [PDF]

Front Cardiovasc Med
Chai H, Huo J, Chen H.
europepmc   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Correction: Management of patients with protein s deficiency: focus on clinical course and direct oral anticoagulants. [PDF]

Thromb J
Altamura N, Di Girolamo FG, Pradella P, Cavalet M, Pellicori F, Vinci P, Panizon E, Cominotto G, Zaccari M, Galasso I, La Rocca P, Teraž K, La Raja M, Fiotti N, Biolo G.   +14 more
europepmc   +1 more source

Comparative Outcomes of Fine Needle Aspiration and Core Needle Biopsy for Parotid Masses

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the diagnostic accuracy and safety of ultrasound‐guided fine needle aspiration (FNA) versus core needle biopsy (CNB) for parotid masses. Study Design Retrospective cohort study. Setting Tertiary academic medical center, 2018 to 2023. Methods We reviewed 485 patients undergoing ultrasound‐guided parotid biopsy (426 FNAs and
Lisa Eleni Chionis Buhler, Andrew Prince, Nicholas Bunda, Kimberly Oslin, Joshua Smith, Michael Allevato, Emma Hershey, Steven B. Chinn, Mark E. P. Prince   +8 more
wiley   +1 more source

Trend of Reported Bleeding in Warfarin Compared with Direct Oral Anticoagulants in Japan. [PDF]

Drug Healthc Patient Saf
Takami A, Terashima G, Tajima T, Yamashita K, Igarashi A.   +4 more
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Left Atrial Appendage Closure vs Direct Oral Anticoagulants in Atrial Fibrillation: Meta-Analysis of Randomized Trials. [PDF]

JACC Adv
Chan YH, Cheng WH, Yeh YH, Kuo L, Liu CM, Liao JN, Hung CL, Lip GYH, Chao TF.   +8 more
europepmc   +1 more source

Comparing leukocyte‐ and thrombocyte‐rich fibrin and autologous grafts for the treatment of experimentally induced wounds in the tarsometatarsus of chickens

Veterinary Record, EarlyView.
Abstract Background Managing open wounds in birds is challenging. This study compared leukocyte‐ and thrombocyte‐rich fibrin (L‐TRF) and autologous grafts for treating wounds in the tarsometatarsus of chickens. Methods Full‐thickness wounds were experimentally induced in the tarsometatarsus of 23 healthy adult chickens.
Vivian Ferreira Rech, Sheila Canevese Rahal, Renata Dalcol Mazaro, Luna Scarpari Rolim, Guilherme Rech Cassanego, Matheus Yuri Dos Santos, Rafael Almeida Fighera   +6 more
wiley   +1 more source

Transfusion and mortality after major trauma in patients on direct oral anticoagulants: a multicentre cohort study. [PDF]

Scand J Trauma Resusc Emerg Med
Wersäll JH, Hedelin H, Vidlund A, Ekdahl E, Kjellberg J, Larsson PU, Normark L, Högberg D.   +7 more
europepmc   +1 more source