Results 211 to 220 of about 67,152 (253)
Some of the next articles are maybe not open access.
Direct Oral Anticoagulants and Women
Seminars in Thrombosis and Hemostasis, 2016Direct oral anticoagulants (DOACs) provide an effective, safe, and convenient therapeutic alternative to warfarin and other vitamin K antagonists (VKAs), and are now established for a wide range of indications. The use of DOACs in women merits special consideration due to two main situations: first, in relation to fertility, pregnancy, and lactation in
Deepa R. J. Arachchillage +4 more
openaire +3 more sources
DeckerMed Critical Care of the Surgical Patient, 2017
Non–vitamin K antagonist oral anticoagulants, also known as direct oral anticoagulants, are a relatively recent class of medications introduced into clinical practice. Due to their safety profiles, fixed dosing, and lack of need for frequent laboratory monitoring, they are becoming preferred to traditional anticoagulation with warfarin in many cases of
Panna A. Codner, Michael G Mount
openaire +1 more source
Non–vitamin K antagonist oral anticoagulants, also known as direct oral anticoagulants, are a relatively recent class of medications introduced into clinical practice. Due to their safety profiles, fixed dosing, and lack of need for frequent laboratory monitoring, they are becoming preferred to traditional anticoagulation with warfarin in many cases of
Panna A. Codner, Michael G Mount
openaire +1 more source
Edoxaban: A direct oral anticoagulant
American Journal of Health-System Pharmacy, 2017The pharmacology, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, and place in therapy of edoxaban for prevention of stroke in patients with nonvalvular atrial fibrillation (AF) and treatment of venous thromboembolism (VTE) are reviewed.Although warfarin has been an established therapy for stroke prevention in AF and VTE, the need for ...
Umima Baig +3 more
openaire +3 more sources
Measuring Direct Oral Anticoagulants
2017Direct oral anticoagulants (DOACs) can be quantified using methods that can be performed in any clinical or research laboratory using manual or automated instrument platforms. Dabigatran etexilate, the oral direct thrombin inhibitor, can be quantified by drug-calibrated clot or chromogenic-based assays using either thrombin or ecarin as substrates ...
Robert C. Gosselin, Jonathan Douxfils
openaire +4 more sources
Direct oral anticoagulants: An update
Medicina Clínica (English Edition), 2018Vitamin K antagonists were the only choice for chronic oral anticoagulation for more than half a century. Over the past few years, direct oral anticoagulants have emerged, including one direct thrombin inhibitor (dabigatran etexilate) and three factor Xa inhibitors (apixaban, edoxaban and rivaroxaban).
Ana Isabel Franco Moreno +2 more
openaire +2 more sources
Direct Oral Anticoagulants in Cirrhosis
Current Treatment Options in Gastroenterology, 2016The risk of thrombosis in patients with chronic liver disease is increasingly recognized. As patients with cirrhosis develop indications for anticoagulation therapy (e.g., venous thromboembolism, portal vein thrombosis, or atrial fibrillation), providers are left to make difficult decisions when selecting therapeutics with little evidence to rely on ...
Hillary S. Maitland +2 more
openaire +3 more sources
Role of Direct Oral Anticoagulants in the Management of Anticoagulation
Southern Medical Journal, 2017For decades, vitamin K antagonists (VKAs) have been the oral treatment of choice for many thromboembolic conditions. The limitations of VKAs include the need for monitoring through blood testing, drug interactions, and narrow therapeutic windows. These shortcomings have led to the development of direct oral anticoagulants.
Suman Rathbun +2 more
openaire +3 more sources
Detection of lupus anticoagulant in the era of direct oral anticoagulants
Autoimmunity Reviews, 2017Lupus anticoagulant (LAC) is an in vitro phenomenon determining a phospholipid-dependent elongation of clotting times. The presence of LAC associated with anticardiolipin (aCL) and anti-β2 glycoprotein I (anti-β2GPI) antibodies is strongly associated with thrombosis and pregnancy morbidity.
HOXHA, ARIELA +3 more
openaire +3 more sources