Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Mechanical Heart Valves: A Systematic Review. [PDF]
Mandefro BT +6 more
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Bleeding prediction scores in patients with venous thromboembolism using direct oral anticoagulants. [PDF]
Wu G +12 more
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Real-world adherence trajectories to direct oral anticoagulants in naive patients with atrial fibrillation in Spain. [PDF]
Leguízamo-Martínez LM +5 more
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Effectiveness of direct oral anticoagulants for all-cause mortality and cardiovascular events in overweight and obese patients with atrial fibrillation: Insight from the nationwide START registry. [PDF]
Menichelli D +7 more
europepmc +1 more source
Efficacy and safety of direct oral anticoagulants versus warfarin in patients with a left ventricular thrombus: an updated systematic review and meta-analysis of randomised controlled trials. [PDF]
Costa TA +6 more
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Non–vitamin K antagonist oral anticoagulants, also known as direct oral anticoagulants, are a relatively recent class of medications introduced into clinical practice. Due to their safety profiles, fixed dosing, and lack of need for frequent laboratory monitoring, they are becoming preferred to traditional anticoagulation with warfarin in many cases of
Michael G Mount, Panna A. Codner
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Measuring Direct Oral Anticoagulants
2017Direct oral anticoagulants (DOACs) can be quantified using methods that can be performed in any clinical or research laboratory using manual or automated instrument platforms. Dabigatran etexilate, the oral direct thrombin inhibitor, can be quantified by drug-calibrated clot or chromogenic-based assays using either thrombin or ecarin as substrates ...
Robert C, Gosselin, Jonathan, Douxfils
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New anticoagulants: Moving beyond the direct oral anticoagulants
Journal of Thrombosis and Haemostasis, 2021Although anticoagulants have been in use for more than 80 years, heparin and vitamin K antagonists were the sole available options until recently. Although these agents revolutionized the prevention and treatment of thrombotic diseases, their use has been hampered by the necessity for coagulation monitoring and by bleeding complications resulting in ...
James C. Fredenburgh, Jeffrey I. Weitz
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Direct Oral Anticoagulants and Women
Seminars in Thrombosis and Hemostasis, 2016Direct oral anticoagulants (DOACs) provide an effective, safe, and convenient therapeutic alternative to warfarin and other vitamin K antagonists (VKAs), and are now established for a wide range of indications. The use of DOACs in women merits special consideration due to two main situations: first, in relation to fertility, pregnancy, and lactation in
Cohen, Hannah +4 more
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