Results 121 to 130 of about 101,128 (285)

Dimension of amalgamated graphs and trees [PDF]

, 1985
For a graph G, dim G is defined to be the least natural number n such that G is an induced subgraph of a categorial (or direct) product of n complete graphs. The dimension of sums of graphs has been studied in [3] and [8].
Alles, Peter
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

On some topological indices of zero divisor graphs of direct product of three finite fields

Examples and Counterexamples
In this paper, we determine some degree-based topological indices, such as the Sombor index, the first and second Zagreb indices, the forgotten topological index, the Narumi–Katayama index, the first and second multiplicative Zagreb indices, the atom ...
Subhash Mallinath Gaded, Nithya Sai Narayana   +1 more
doaj   +1 more source

Union of Distance Magic Graphs

Discussiones Mathematicae Graph Theory, 2017
A distance magic labeling of a graph G = (V,E) with |V | = n is a bijection ℓ from V to the set {1, . . . , n} such that the weight w(x) = ∑y∈NG(x) ℓ(y) of every vertex x ∈ V is equal to the same element μ, called the magic constant.
Cichacz Sylwia, Nikodem Mateusz
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Direct products of complete graphs [PDF]

, 2013
Prvi del disertacije je posvečen neodvisnim dominantnim množicam direktnega produkta štirih polnih grafov. Eksplicitno so opisane T1-množice, tj. množice, kjer se poljubni par vozlišč ujema na natanko enem mestu.
Mekiš, Gašper
core   +1 more source

Product Operations on q-Rung Orthopair Fuzzy Graphs [PDF]

, 2019
The q-rung orthopair fuzzy graph is an extension of intuitionistic fuzzy graph and Pythagorean fuzzy graph. In this paper, the degree and total degree of a vertex in q-rung orthopair fuzzy graphs are firstly defined.
Songyi Yin, Hongxu Li, Yang Yang
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source