Prescriptions Direct: a repeat prescribing scheme pilot study [PDF]
Jill Loader+3 more
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High prevalence of direct repeat unit types of 10di, 8 h and 8i among methicillin resistant Staphylococcus aureus strains with staphylococcal cassette chromosome mec type IIIA isolated in Tehran, Iran. [PDF]
Motallebi M+3 more
europepmc +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Site-directed mutagenesis of conserved inverted repeat sequences in the xylanase C promoter region from Streptomyces sp. EC3 [PDF]
Fabrizio Giannotta+4 more
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Direct Repeat Unit (dru) Typing of Methicillin-Resistant Staphylococcus pseudintermedius from Dogs and Cats. [PDF]
Kadlec K+3 more
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
The Relationship of CAC Polymorphism in HOXA1 Gene and Breast Cancer
Background: HOXA1 is a transcription factor. In the human mammary gland, the expression of the HOXA1 gene is very low or absent during normal growth and differentiation, but it is expensed at high levels in breast cancer lesions.
Somaye Najafi-Dorche+3 more
doaj
The Effect of Sequence Divergence on Recombination Between Direct Repeats in Arabidopsis [PDF]
Roy Opperman+2 more
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
A Fragment of21ORFs Around the Direct Repeat (DR) Region ofMycobacterium tuberculosisis Absent From the Other Sequenced Mycobacterial Genomes: Implications for the Evolution of the DR Region [PDF]
Karina Caimi, Angel Cataldi
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