Results 41 to 50 of about 1,569,399 (342)

Instability of large direct repeats in retrovirus vectors [PDF]

Journal of Virology, 1987
Retrovirus vectors were constructed with large (0.85- to 1.3-kilobase-pair) direct repeats in their genomes. Deletions involving the direct repeats occurred at a high frequency. Deletions occurred both when the direct repeats were in tandem and when they were separated by additional sequences. These deletions occurred during virus replication.
B W, Rhode, M, Emerman, H M, Temin
openaire   +2 more sources

Surface topography of microtubule walls decorated with monomeric and dimeric kinesin constructs [PDF]

, 2000
The surface topography of opened-up microtubule walls (sheets) decorated with monomeric and dimeric kinesin motor domains was investigated by freeze-drying and unidirectional metal shadowing.
Doerhoefer, Monika, Gross, Heinz, Hoenger, Andreas, Mandelkow, Eckhard, Song, Young Hwa, Tittmann, Peter, Woehlke, Guenther   +6 more
core   +2 more sources

Targeted Control of Gene Expression Using CRISPR-Associated Endoribonucleases

Cells
CRISPR-associated endoribonucleases (Cas RNases) cleave single-stranded RNA in a highly sequence-specific manner by recognizing and binding to short RNA sequences known as direct repeats (DRs).
Sagar J. Parikh, Heather M. Terron, Luke A. Burgard, Derek S. Maranan, Dylan D. Butler, Abigail Wiseman, Frank M. LaFerla, Shelley Lane, Malcolm A. Leissring   +8 more
doaj   +1 more source

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal [PDF]

, 2013
Embryonic stem (ES) cell self-renewal efficiency is determined by the Nanog protein level. However, the protein partners of Nanog that function to direct self-renewal are unclear.
Alessia Gagliardi, Ambrosetti DC, Ambrosetti DC, Anastasia Felker, Anastasia I Kousa, Avilion AA, Bailey TL, Bogan AA, Brookes E, Chambers I, Chambers I, Chen X, Chen X, Costa Y, DeLano WL, Dignam JD, Douglas Colby, Engelen E, Favaro R, Festuccia N, Fidalgo M, Florian Halbritter, Gao Z, Genzor CG, Halbritter F, Han JD, Harley VR, Hatano SY, Ho SN, Hooper M, Hutchins AP, Ian Chambers, Jang H, Jason T Weiss, Jauch R, Jepsen K, Jeroen Demmers, Karel Bezstarosti, Kim J, Laemmli UK, Lam CS, Liang J, Ma T, Marson A, Maruyama M, Masui S, McDonel P, Mitsui K, Moretto-Zita M, Mullin NP, Navarro P, Navarro P, Nicholas P Mullin, Noble SM, Pardo M, Parisi S, Perkins DN, Qin J, Raymond A Poot, Rebecca Favaro, Remenyi A, Reynolds N, Rogers MS, Rugg-Gunn PJ, Shi W, Silvia K Nicolis, Simon R Tomlinson, Singh AM, Smith AG, Surface LE, Ura H, van den Berg DL, Wang J, Wang Z, Whyte WA, Wu Q, Yates A, Yuan H, Zappone MV, Zi Ying Tan   +79 more
core   +1 more source

Predominant Tuberculosis Spoligotypes, Delhi, India

Emerging Infectious Diseases, 2004
One hundred five Mycobacterium tuberculosis clinical isolates from the Delhi area were typed by spoligotyping; 45 patterns were identified. Comparison with an international spoligotype database showed type 26, Delhi type (22%), type 54 (12%), and type 1,
Urvashi Balbir Singh, Naga Suresh, N.Vijaya Bhanu, Jyoti Arora, Hema Pant, Sanjeev Sinha, Ram Charan Aggarwal, Sushma Singh, Jitendra Nath Pande, Christophe Sola, Nalin Rastogi, Pradeep Seth   +11 more
doaj   +1 more source

Women’s Perceptions of Caesarean Birth: A Roy International Study [PDF]

, 2011
The purpose of this Roy adaptation model-based multi-site international mixed method study was to examine the relations of type of caesarean birth (unplanned/planned), number of caesarean births (primary/repeat), and preparation for caesarean birth to ...
Aber, Cynthia, Astedt-Kurki, Paivi, Fawcett, Jacqueline, Hall, Jaye L., Haussler, Susan, King, Charlette, Myers, Sheila Taylor, Newton, Jennifer, Rantanen, Anja, Silva, Virginia, Tarkka, Marja-Terttu, Waters, V. Lynn, Weiss, Marianne   +12 more
core   +2 more sources

Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]

, 2012
BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen, Fang, Yaping, He, Yuqi, Liu, Hui-Xin, Wan, Yu-Jui Yvonne, Zhan, Qi   +5 more
core   +5 more sources

Quantum corrections from a path integral over reparametrizations

, 2010
We study the path integral over reparametrizations that has been proposed as an ansatz for the Wilson loops in the large-$N$ QCD and reproduces the area law in the classical limit of large loops.
A. M. Polyakov, I. S. Gradshteyn, J. Douglas, N. W. McLachlan, P. Buividovich, Poul Olesen, Yuri Makeenko   +6 more
core   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source