Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
SSA-like and MMEJ-like recombination events in a transgenic construct with in-cis programmed self-eliminating components in different E. coli strains. [PDF]
Ogaugwu CE, Adelman ZN.
europepmc +1 more source
Comparison of Direct Models with Conventional Sequence Models for Travel Demand Estimation
Katsutoshi Ota, Yoriyasu Sugie
openalex +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Sequential model predictive direct speed control of PMSM. [PDF]
Pancurák L, Horváth K, Kyslan K.
europepmc +1 more source
Breaking a chaotic direct sequence spreading spectrum secure communication system
HU Jin-feng +2 more
openalex +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
First-Attempt Intubation Success Rate Using the C-MAC Videolaryngoscope Versus Direct Laryngoscopy Among Anaesthesiology Residents Performing Rapid Sequence Induction: A Randomised Controlled Trial. [PDF]
Lava Kumar P +5 more
europepmc +1 more source

