Results 51 to 60 of about 64,829 (253)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A CHEAP ZILOG MP APPLIED TO SPREAD SPECTRUM SYSTEMS DESIGN
The Z2000 Evaluation Board performing direct sequence spread spectrum processing, a 900 MHz radio receiver, and a transmitter module was applied to build a Direct sequence spread spectrum transceiver, RF board was designed & implemented for the purpose ...
Rajaa aldeen Abad Khalid
doaj
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Performance of Direct Sequence Spread Spectrum System (DSSSS) in Presence of Single and Multi Tone Jamming [PDF]
There are various impairments or problems on direct sequence spread spectrum communication channel especially jamming problems, in order to focus on this problem a direct sequence spread spectrum(DSSS) communication system using Gold code was used as ...
Sadiq Kamel Gharkan +2 more
doaj +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Detection of Signals with Chaotic Varying Forms and Low Intercept Probability
Low probability of intercept performance of direct-sequence spread-spectrum system with chaotic spreading sequences is investigated. The energy detectors, synchronous and asynchronous, coherent and non-coherent structures are studied here to detect the ...
V. Р. Tuzlukov
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Optimum Combining for Coherent FFH/DS Spread Spectrum Receivers in the Presence of Multi-Tone Jammer
Fast Frequency Hopping/Direct Sequence (FFH/DS) hybrid spread spectrum is an effective technique of the communication network for the robot swarms operating in complex electromagnetic environment.
Shixun Luo +5 more
doaj +1 more source

