Results 51 to 60 of about 234,352 (292)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Process Optimization and Distortion Prediction in Directed Energy Deposition

Journal of Manufacturing and Materials Processing
Directed energy deposition (DED), a form of additive manufacturing (AM), is gaining traction for its ability to produce complex metal parts with precise geometries.
Adem Ben Hammouda, Hatem Mrad, Haykel Marouani, Ahmed Frikha, Tikou Belem   +4 more
doaj   +1 more source

Extension and its characteristics of ECRH plasma in the LHD

, 2004
One of the main objectives of the LHD is to extend the plasma confinement database for helical systems and to demonstrate such extended plasma confinement properties to be sustained in steady state.
A Komori, A Sagara, Alejaldre C, B J Peterson, Bornatici M, H Funaba, H Idei, H Nakanishi, H Yamada, I Yamada, Iiyoshi A, J Miyazawa, K Ida, K Ikeda, K Itoh, K Kawahata, K Khlopenkov, K Nagaoka, K Narihara, K Nishimura, K Ohkubo, K Saito, K Tanaka, K Toi, K Tsumori, K Watanabe, K Yamazaki, Kubo S, Kubo S, M Emoto, M Goto, M Isobe, M Nishiura, M Osakabe, M Shoji, M Yokoyama, M Yoshinuma, Maassberg H, N Ashikawa, N Noda, N Ohyabu, N Takeuchi, N Tamura, Notake T, O Kaneko, O Motojima, R Kumazawa, R Sakamoto, S Inagaki, S Kubo, S Masuzaki, S Morita, S Murakami, S Muto, S Ohdachi, S Sakakibara, S Sudo, Shimozuma T, Shimozuma T, T Ido, T Kobuchi, T Minami, T Morisaki, T Mutoh, T Notake, T Ozaki, T Seki, T Shimozuma, T Tokuzawa, T Watanabe, T Watari, Y Hamada, Y Nagayama, Y Nakamura, Y Narushima, Y Oka, Y Takeiri, Y Yoshimura, Yokoyama M   +78 more
core   +1 more source

Direction dependency in coaxial laser double wire Direct Energy Deposition

Procedia CIRP, 2022
Coaxial Laser wire Direct Energy Deposition (L-DED) promises a direction-independent buildup due to a centric supply of the welding material. To fabricate Functionally Graded Materials (FGMs), a processing head was designed that is capable of supplying two wire materials into the processing zone.
Schwarz, Nick, Lammers, Marius, Hermsdorf, Jörg, Kaierle, Stefan, Ahlers, Henning, Lachmayer, Roland   +5 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Resource efficiency in high-value material manufacturing with directed energy deposition [PDF]

MATEC Web of Conferences
Manufacturing high-value materials often yields excessive waste, high costs, and lengthy lead times using traditional methods. Directed Energy Deposition (DED) offers a sustainable alternative by reducing material waste, machining time, and tool ...
Strauss Jacques, Hagedorn-Hansen Devon, Becker Thorsten H.   +2 more
doaj   +1 more source

A Review on Wire-Fed Directed Energy Deposition Based Metal Additive Manufacturing

Journal of Manufacturing and Materials Processing, 2023
Metal additive manufacturing has reached a level where products and components can be directly fabricated for applications requiring small batches and customized designs, from tinny body implants to long pedestrian bridges over rivers.
Tuğrul Özel, Hamed Shokri, Raphaël Loizeau   +2 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

The Reusability of AlSi10Mg Powder in Directed Energy Deposition

Powders
The low deposition efficiency in directed energy deposition (DED) has prompted the reuse of powders that do not fuse to the builds to make additive manufacturing more sustainable.
Parnian Kiani, Alexander D. Dupuy, Kaka Ma, Julie M. Schoenung   +3 more
doaj   +1 more source