Results 61 to 70 of about 234,352 (292)

Ti6Al4V Thin Walls Production using Laser Directed Energy Deposition (L-DED) Process

International Journal of Engineering Materials and Manufacture, 2021
One of the main applications of Directed Energy Deposition (DED) is the production of thin-wall structures, where it has significant advantages over traditional milling and machining techniques, or even welded analogues.
German Barragan, Fabio Mariani, Reginaldo Coelho   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Is keV ion induced pattern formation on Si(001) caused by metal impurities?

, 2010
We present ion beam erosion experiments performed in ultra high vacuum using a differentially pumped ion source and taking care that the ion beam hits the Si(001) sample only.
Bashkim Ziberi, Carter G, Daniel F Förster, Fan W B, Fan W B, Fouckhardt H, Frank Frost, Gago R, Keller A, Ozaydin-Ince G, Polop C, Sven Macko, Sánchez-García J A, Sánchez-García J A, Teichert C, Thomas Michely, Wilson S J, Zhang K, Ziberi B   +18 more
core   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Tailoring microstructure using pulsed electromagnetic field-assisted directed energy deposition

Materials Today Advances
Despite the advancements in laser directed energy deposition, challenges such as micro-segregation, formation of hard and brittle phases, and poor controllability over solidification microstructures persist due to the rapid melting-solidification ...
Hao Fang, Pengzhi Zhang, Honghao Ge, Jang Griffin, Gang Dong, Huaping Wu, Liang Wang, Jianhua Yao, Chinnapat Panwisawas   +8 more
doaj   +1 more source

Excellent superelasticity in a Co-Ni-Ga high-temperature shape memory alloy processed by directed energy deposition

Materials Research Letters, 2020
A Co-Ni-Ga high-temperature shape memory alloy has been additively manufactured by directed energy deposition. Due to the highly anisotropic microstructure, i.e.
C. Lauhoff, N. Sommer, M. Vollmer, G. Mienert, P. Krooß, S. Böhm, T. Niendorf   +6 more
doaj   +1 more source

Development of an intense positron source using a crystal--amorphous hybrid target for linear colliders

, 2013
In a conventional positron source driven by a few GeV electron beam, a high amount of heat is loaded into a positron converter target to generate intense positrons required by linear colliders, and which would eventually damage the converter target.
Akagi, T., Chehab, R., Dadoun, O., Furukawa, K., Kamitani, T., Kawada, S., Omori, T., Satoh, M., Strakhovenko, V., Suwada, T., Takahashi, T., Uesugi, Y., Umemori, K., Urakawa, J., Variola, A.   +14 more
core   +3 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Site-Specific Colloidal Crystal Nucleation by Template-enhanced Particle Transport

, 2016
The monomer surface mobility is the single most important parameter that decides the nucleation density and morphology of islands during thin film growth.
Ganapathy, Rajesh, Mishra, Chandan K, Sood, A K   +2 more
core   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source