Results 61 to 70 of about 58,702 (295)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Partitioning of laser energy during directed energy deposition

Additive Manufacturing, 2017
Abstract An energy balance that describes the transfer of energy is proposed for the laser-based directed energy deposition process. The partitioning of laser energy was experimentally measured and accurately validated using a special process calorimeter for Ti-6Al-4V and Inconel 625™ alloys. The total energy provided by the laser was partitioned as:
Frederick Lia, Joshua Park, Jay Tressler, Richard Martukanitz   +3 more
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Resource efficiency in high-value material manufacturing with directed energy deposition [PDF]

MATEC Web of Conferences
Manufacturing high-value materials often yields excessive waste, high costs, and lengthy lead times using traditional methods. Directed Energy Deposition (DED) offers a sustainable alternative by reducing material waste, machining time, and tool ...
Strauss Jacques, Hagedorn-Hansen Devon, Becker Thorsten H.   +2 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Excellent superelasticity in a Co-Ni-Ga high-temperature shape memory alloy processed by directed energy deposition

Materials Research Letters, 2020
A Co-Ni-Ga high-temperature shape memory alloy has been additively manufactured by directed energy deposition. Due to the highly anisotropic microstructure, i.e.
C. Lauhoff, N. Sommer, M. Vollmer, G. Mienert, P. Krooß, S. Böhm, T. Niendorf   +6 more
doaj   +1 more source

Design Considerations for a Directed Energy Deposition Cell

, 2023
Setting up a robotised additive manufacturing machine requires attention to several safety aspects, including integration of different systems, a functional work area, human-machine interfaces and convenience in operation. This article presents some topics that should be considered in the design and assembly of a cell for robotised additive ...
Hassel, Trond Arne, Brøtan, Vegard, Sørby, Knut   +2 more
openaire   +3 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

JEMA-SINDYc: End-to-end Control using Joint Embedding Multimodal Alignment in Directed Energy Deposition

Bringing AI models from digital to real-world applications presents significant challenges due to the complexity and variability of physical environments, often leading to unexpected model behaviors. We propose a framework that learns to translate images
Brandau, Benedikt, Brueckner, Frank, Reis, Luís Paulo, Sousa, Armando, Darabi, Roya, Hemschik, Rico, Reis, Ana, Brückner, Frank, Meireles De Sousa, Joao Paulo, Sousa, João   +9 more
core   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source