Results 41 to 50 of about 832,082 (275)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Convert a Strongly Connected Directed Graph to a Black-and-White 3-SAT Problem by the Balatonboglár Model

open access: yesAlgorithms, 2020
In a previous paper we defined the black and white SAT problem which has exactly two solutions, where each variable is either true or false. We showed that black and white 2-SAT problems represent strongly connected directed graphs. We presented also the
Gábor Kusper, Csaba Biró
doaj   +1 more source

Counting Hamilton cycles in sparse random directed graphs

open access: yes, 2018
Let D(n,p) be the random directed graph on n vertices where each of the n(n-1) possible arcs is present independently with probability p. A celebrated result of Frieze shows that if $p\ge(\log n+\omega(1))/n$ then D(n,p) typically has a directed Hamilton
Alon book N.   +7 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Quantitation of Vascular Morphology by Directed Graph Construction

open access: yesIEEE Access, 2019
The quantitation of morphology information of X-ray angiography image has an important value in the diagnosis of coronary artery disease. This paper proposes an automatic morphology estimation method by using directed graph construction for X-ray ...
Jingliang Zhao   +5 more
doaj   +1 more source

Directed path graphs [PDF]

open access: yes, 1996
The concept of a line digraph is generalized to that of a directed path graph. The directed path graph $\overrightarrow P_k(D)$ of a digraph D is obtained by representing the directed paths on k vertices of D by vertices.
Broersma, Hajo, Li, Xueliang
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Applications of Multivalued Contractions on Graphs to Graph-Directed Iterated Function Systems

open access: yesAbstract and Applied Analysis, 2015
We apply a fixed point result for multivalued contractions on complete metric spaces endowed with a graph to graph-directed iterated function systems.
T. Dinevari, M. Frigon
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Unknown Vulnerability Risk Assessment Based on Directed Graph Models: A Survey

open access: yesIEEE Access, 2019
Nowadays, vulnerability attacks occur frequently. Due to the information asymmetry between attackers and defenders, vulnerabilities can be divided into known and unknown.
Wenhao He, Hongjiao Li, Jinguo Li
doaj   +1 more source

Home - About - Disclaimer - Privacy