Results 51 to 60 of about 839,618 (278)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Applications of Multivalued Contractions on Graphs to Graph-Directed Iterated Function Systems

open access: yesAbstract and Applied Analysis, 2015
We apply a fixed point result for multivalued contractions on complete metric spaces endowed with a graph to graph-directed iterated function systems.
T. Dinevari, M. Frigon
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Unknown Vulnerability Risk Assessment Based on Directed Graph Models: A Survey

open access: yesIEEE Access, 2019
Nowadays, vulnerability attacks occur frequently. Due to the information asymmetry between attackers and defenders, vulnerabilities can be divided into known and unknown.
Wenhao He, Hongjiao Li, Jinguo Li
doaj   +1 more source

The nucleolus of directed acyclic graph games [PDF]

open access: yes, 2013
In this paper we consider a natural generalization of standard tree games where the underlying structure is a directed acyclic graph. We analyze the properties of the game and illustrate its relation with other graph based cost games.
Fleiner, Tamás   +2 more
core  

Covering Directed Graphs by In-Trees [PDF]

open access: yesJournal of Combinatorial Optimization, 2008
15 pages, 12 ...
Naoyuki Kamiyama, Naoki Katoh
openaire   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The diameter of directed graphs

open access: yesJournal of Combinatorial Theory, Series B, 2005
Let \(D\) be a strongly connected Eulerian oriented graph with \(n\) vertices and minimum out-degree \(\delta\). The author shows that the diameter of \(D\) is at most \(4n/(2\delta+ 1)+ 2\). This bound, which strengthens an earlier bound by \textit{A. V. Knyazev} [Mat.
openaire   +2 more sources

Directed random geometric graphs [PDF]

open access: yesJournal of Complex Networks, 2019
Abstract Many real-world networks are intrinsically directed. Such networks include activation of genes, hyperlinks on the internet and the network of followers on Twitter among many others. The challenge, however, is to create a network model that has many of the properties of real-world networks such as power-law degree distributions ...
Jesse Michel   +4 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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