Results 81 to 90 of about 382,964 (309)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Exploratory and directed search strategies at a social science data archive
IASSIST QuarterlyResearchers need to be able to find, access, and use data to participate in open science. To understand how users search for research data, we analyzed textual queries issued at a large social science data archive, the Inter-university Consortium for ...
Sara Lafia, A.J. Million, Libby Hemphill
doaj +1 more source
Interação em Psicologia, 2008 A importância das pesquisas que visam desenvolver, validar e adaptar instrumentos de avaliação psicológica se dá no sentido de oferecer condições apropriadas de trabalho aos profissionais da Psicologia, especialmente no domínio da Orientação Profissional,
Ana Paula Porto Noronha +1 more
doaj +1 more source
Greedoids and searches in directed graphs
Discrete Mathematics, 1991 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Directed search, unemployment and public policy [PDF]
Canadian Journal of Economics/Revue canadienne d'économique, 2009 Abstract We examine the effects of public policy parameters in a simple directed search model of the labour market, and contrast them with those in standard random matching models with Nash bargaining. Both finite and limit versions of the directed search model are considered, and the value of the limit model as an approximation of the finite one is ...
Kennes, John +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A Survey of Search Strategies in the Dynamic Symbolic Execution
ITM Web of Conferences, 2017 Dynamic symbolic execution (DSE) is an important way to discover software vulnerabilities. One key challenge in DSE is to find proper paths in the huge program execution space to generate effective inputs.
Liu Yu, Zhou Xu, Gong Wei-Wei
doaj +1 more source
Search for a direction in the forest of Lyman-α [PDF]
Journal of Cosmology and Astroparticle Physics, 2015 16 pages, 5 figures, 2 ...
Hazra, Dhiraj Kumar, Shafieloo, Arman
openaire +2 more sources
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source