A study to define the need for integrating elements of administration into the basic curriculum of professional nurse education [PDF]
, 1958 Thesis (M.S.)--Boston ...
Defenderfer, Julia B.
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Geminal group-directed olefinic C-H functionalization via four- to eight-membered exo-metallocycles
Nature Communications, 2019 Identifying distinct cyclometallation pathways is essential to new types of C-H activation and functionalization in organic synthesis. Here, the authors show the activation of an olefinic C-H bond geminal to the directing group via four- to eight ...
Keke Meng +5 more
doaj +1 more source
Enantioselective Hydroalkenylation and Hydroalkynylation of Alkenes Enabled by a Transient Directing Group: Catalyst Generality through Rigidification. [PDF]
Angew Chem Int Ed Engl, 2023 Simlandy AK +7 more
europepmc +1 more source
A Biologist’s View of Individual Cultural Identity for the Study of Cities [PDF]
The behaviour of urban populations is compared with the systems directing behaviour in individuals. This is both a metaphor and a mechanistic parallel. The biological model draws upon recent developments in brain research and psychological and cultural ...
Richard Pearce
core
Training in the technique of study [PDF]
, 1924 Bibliography: p.
Mohlman, Dora, Monroe, Walter Scott
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Directing-Group-Free Arene C(sp2)-H Amination Using Bulky Aminium Radicals and DFT Analysis of Regioselectivity. [PDF]
J Org Chem, 2023 Behnke NE +4 more
europepmc +1 more source