Results 111 to 120 of about 19,002,772 (320)
A Pdᴵᴵ-catalyzed, ligand-enabled gamma-C(sp3)–H arylation of free primary aliphatic amines and amino esters without using an exogenous directing group is reported.
Gang, Li +4 more
core +1 more source
On directed interpolation groups [PDF]
Radical classes of lattice-ordered groups (\(\ell\)-groups) have been the subject of many researchers in recent years most notably the present author. Here, an important extension of these ideas is introduced in the study of radical classes of directed interpolation groups. [See \textit{L. Fuchs}, Ann. Sc. Norm. Sup. Pisa, Cl. Sci. Fis. Mat., III. Ser.
openaire +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Cowboys Directing a Group of Cattle
A sepia photograph depicting two unidentified cowboys on horseback, directing a group of cows in front them a certain ...
Dixon, Maynard
core +2 more sources
A unified approach for divergent synthesis of contiguous stereodiads employing a small boronyl group
Predictable and unified approaches to all possible stereoisomers of acyclic compounds with contiguous stereocentres are rare. Here, the authors disclose a divergent α-functionalization of enolates with either syn or anti selectivity employing a β-boronyl
Miao Zhan +10 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Inherent directing group enabled, Co(III)-catalyzed C-H allylation/ vi-nylation of isoquinolones
The site-selective C8-allylation and vinylation of isoquinolones have been accomplished using allyl acetate and vinyl acetate and oxo group of isoquinolone as an inherent directing group in the presence of Co(III) catalysis. A plausible mechanism for the
Tamanna , Sharma +3 more
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

