Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Directing group assisted para-selective C-H alkynylation of unbiased arenes enabled by rhodium catalysis. [PDF]
Chem Sci, 2023 Dutta U +5 more
europepmc +1 more source
Kinetic resolution of racemic {alpha}-olefins with ansa-zirconocene polymerization catalysts: Enantiomorphic site vs. chain end control [PDF]
, 2006 Copolymerization of racemic {alpha}-olefins with ethylene and propylene was carried out in the presence of enantiopure C1-symmetric ansa metallocene, {1,2-(SiMe2)2({eta}5-C5H-3,5-(CHMe2)2)({eta}5-C5H3)}ZrCl2 to probe the effect of the polymer chain end ...
Bercaw, John E., Byers, Jeffery A.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
High-resolution directed human connectomes and the Consensus Connectome Dynamics.
PLoS ONE, 2019 Here we show a method of directing the edges of the connectomes, prepared from HARDI datasets from the human brain. Before the present work, no high-definition directed braingraphs were published, because the tractography methods in use are not capable ...
Balázs Szalkai +3 more
doaj +1 more source
Directing-group-free catalytic dicarbofunctionalization of unactivated alkenes. [PDF]
Nat Chem, 2022 Wang H +4 more
europepmc +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Cobalt-catalyzed peri-selective alkoxylation of 1-naphthylamine derivatives
Beilstein Journal of Organic Chemistry, 2018 A cobalt-catalyzed C(sp2)–H alkoxylation of 1-naphthylamine derivatives has been disclosed, which represents an efficient approach to synthesize aryl ethers with broad functional group tolerance.
Jiao-Na Han +7 more
doaj +1 more source
An endo-Directing-Group Strategy Unlocks Enantioselective (3+1+2) Carbonylative Cycloadditions of Aminocyclopropanes. [PDF]
Angew Chem Int Ed Engl, 2022 Sokolova OO, Bower JF.
europepmc +1 more source
, 2002 This is the concert program of the Boston University Opera Institute and Boston University Chamber Orchestra performance of Die Fledermaus by Johann Strauss, running Thursday, April 18 to Saturday, April 2, 2002 at 8:00 p.m. and Sunday, April 21, 2002 at
School of Music, Boston University
core