FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
PdII -Catalyzed C(alkenyl)-H Activation Facilitated by a Transient Directing Group. [PDF]
Angew Chem Int Ed Engl, 2022 Liu M +6 more
europepmc +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Author Correction: Directing-group-free catalytic dicarbofunctionalization of unactivated alkenes. [PDF]
Nat Chem, 2022 Wang H +4 more
europepmc +1 more source
Consumer Direction of Personal Assistance Services in Medicaid: A Review of Four State Programs [PDF]
, 2008 Discusses eligibility for and use of Consumer Direction of Personal Assistance Services, which give beneficiaries control over the hiring, scheduling, training and paying of personal care attendants, in California, Colorado, New York, and ...
Henry Claypool, Molly O'Malley
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Amine-Catalyzed Copper-Mediated C-H Sulfonylation of Benzaldehydes via a Transient Imine Directing Group. [PDF]
Angew Chem Int Ed Engl, 2022 Higham JI, Bull JA.
europepmc +1 more source
Component Group Diagnosability Via Directional Resolution
IFAC proceedings volumes, 2009 Abstract This paper addresses simplification of diagnostic models of systems that can be described in propositional logic. Performing diagnostics on the entire model of a system when only a few variables are expected to be observed, is not efficient.
openaire +1 more source
Generative dramaturgy : a strategy for refocusing directorial intent in the translation phase of play development [PDF]
, 2008 Includes abstract.Includes bibliographical references (leaves 36-40).This explication focuses on the director working collaboratively in the ensemble towards generating new material inspired by the play text in the staging of the play.
Kirch, Michael A
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source