Results 151 to 160 of about 679,253 (302)

Rhodium(i)-catalyzed cascade C(sp²)-H bond alkylation - amidation of anilines: phosphorus as traceless directing group. [PDF]

Chem Sci, 2023
Peng M, Ari D, Roisnel T, Doucet H, Soulé JF.   +4 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Positive Psychotherapy tools in groups

The Global Psychotherapist
In Positive group therapy, certain tools can be used to moderate and guide the process and interactions, directing them toward specific topics: the use of stories and proverbs as narrative tools; visualization tools like the four areas of body ...
Arno Remmers
doaj   +1 more source

Iridium catalysed C2 site-selective methylation of indoles using a pivaloyl directing group through weak chelation-assistance. [PDF]

RSC Adv, 2023
Kathiravan S, Zhang T, Nicholls IA.
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Directing group assisted rhodium catalyzed meta-C-H alkynylation of arenes. [PDF]

Chem Sci, 2022
Sasmal S, Prakash G, Dutta U, Laskar R, Lahiri GK, Maiti D.   +5 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Interplay between the Directing Group and Multifunctional Acetate Ligand in Pd-Catalyzed anti-Acetoxylation of Unsymmetrical Dialkyl-Substituted Alkynes. [PDF]

ACS Catal, 2022
Corpas J, Arpa EM, Lapierre R, Corral I, Mauleón P, Arrayás RG, Carretero JC.   +6 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transient directing group enabled Pd-catalyzed C-H oxygenation of benzaldehydes and benzylic amines. [PDF]

RSC Adv, 2022
Tian M, Shao L, Su X, Zhou X, Zhang H, Wei K, Sun R, Wang J.   +7 more
europepmc   +1 more source