A Transient Directing Group Strategy Enables Enantioselective Multicomponent Organofluorine Synthesis. [PDF]
J Am Chem Soc, 2021 The vicinal fluorofunctionalization of alkenes represents an expedient strategy for converting feedstock olefins into valuable fluorinated molecules and as such has garnered significant attention from the synthetic community; however, current methods ...
Liu Z +6 more
europepmc +4 more sources
A Simple and Versatile Amide Directing Group for C−H Functionalizations [PDF]
Angewandte Chemie - International Edition, 2016 Jin-Quan Yu
exaly +2 more sources
Copper-mediated oxidative C−H/N−H activations with alkynes by removable hydrazides
Beilstein Journal of Organic Chemistry, 2021 The efficient copper-mediated oxidative C–H alkynylation of benzhydrazides was accomplished with terminal alkynes. Thus, a heteroaromatic removable N-2-pyridylhydrazide allowed for domino C–H/N–H functionalization.
Feng Xiong +7 more
doaj +1 more source
Synthesis of Polysubstituted Ferrocenesulfoxides
Molecules, 2022 The purpose of the study is to design synthetic methodologies, especially directed deprotometalation using polar organometallic reagents, to access polysubstituted ferrocenesulfoxides.
Min Wen +6 more
doaj +1 more source
Set-direct factorizations of groups [PDF]
Journal of Algebra, 2018 referee comments included, 19 ...
Levy, Dan, Maróti, Attila
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Catalyst design in C-H activation: a case study in the use of binding free energies to rationalise intramolecular directing group selectivity in iridium catalysis. [PDF]
Chem Sci, 2021 Remote directing groups in a bifunctional molecule do not always behave independently of one another in C–H activation chemistries. A combined DFT and experimental mechanistic study to provide enhanced Ir catalysts for chemoselective C–H deuteration of ...
Kerr WJ, Knox GJ, Reid M, Tuttle T.
europepmc +4 more sources
Grouping with Directed Relationships [PDF]
, 2001 Grouping is a global partitioning process that integrates local cues distributed over the entire image. We identify four types of pairwise relationships, attraction and repulsion, each of which can be symmetric or asymmetric. We represent these relationships with two directed graphs.
Stella X. Yu, Jianbo Shi
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Imine as a linchpin approach for meta-C–H functionalization
Nature Communications, 2021 Site-selective C–H functionalization still faces some challenges, such as the introduction and removal of an appropriate directing group. Here, the authors introduce a temporary directing group for selective meta-C–H functionalization of 2 ...
Sukdev Bag +6 more
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Distal Functionalization via Transition Metal Catalysis
Chemistry Proceedings, 2022 The ubiquitous presence of sp3 C−H bonds in natural feedstock makes them inexpensive, easily accessible, and attractive synthons for the preparation of common and/or complex molecular frameworks in biologically active natural products, pharmaceutics ...
Haibo Ge
doaj +1 more source
Tuning Reactivity in Pd-Catalysed C(sp3)-H Arylations via Directing Group Modifications and Solvent Selection [PDF]
, 2020 The palladium-catalysed sp3 C-H arylation of a selection of saturated amine scaffolds was investigated using substituted picolinamide directing groups.
Abil, Aliev +4 more
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