Catalytic Undirected Meta‐Selective C–H Borylation of Metallocenes
Advanced Science, 2023 Metallocenes are privileged backbones in the fields of synthetic chemistry, catalysis, polymer science, etc. Direct C–H functionalization is undoubtedly the simplest approach for tuning the properties of metallocenes.
Hao Zheng +6 more
doaj +1 more source
Enantioselective Hydroalkenylation and Hydroalkynylation of Alkenes Enabled by a Transient Directing Group [PDF]
, 2022 The catalytic enantioselective synthesis of α-chiral alkenes and alkynes represents a powerful strategy for rapid generation of molecular complexity. Herein, we report a transient directing group facilitated site-selective palladium-catalyzed reductive ...
Quynh, Wong +11 more
core +2 more sources
Pd(II)-Catalyzed Synthesis of Benzocyclobutenes by β-Methylene-Selective C(sp3)‒H Arylation with a Transient Directing Group [PDF]
, 2021 Methylene-selective C‒H functionalization is a significant hurdle that remains to be addressed in the field of Pd(II) cataly-sis. In this paper we report a Pd(II) catalyzed synthesis of benzocyclobutenes by methylene-selective C(sp3)‒H arylation of ...
Jonathan, Wong +6 more
core +1 more source
Directing-Group-Assisted Non-Strained Ether C–O Bond Homolysis Mediated by Low-Valent Titanium
Ether C–O bonds are typical constituents of organic molecules that are seldom regarded as reactive functional groups except when highly strained. With the assistance of appropriate directing groups, low-valent titanium was found to homolytically cleave ...
Yutaka Ukaji (1589830) +3 more
core +3 more sources
, 2020 A new type of coupling between unactivated olefins and nonstabilized alkyl radicals was achieved, which enabled the first intermolecular Heck-type reaction of cycloketone oxime esters and unactivated alkenes.
Gui-Juan Cheng (1855090) +6 more
core +1 more source
New Transient Directing Group: Diethoxyethyl-L-Proline Facilitate Mono ortho-Arylation at Ar-yl-Amines/-Amino acids via Pd-Catalysed C(sp2)-H Activation [PDF]
, 2022 The mono-ortho-arylated arylamines are constituents of various natural products but their syntheses are challenging. This report describes the new synthetic methodology for mono-ortho-arylation of aryla-mines and α-aromatic amino acids (Phenyl glycine ...
Nagendra, Sharma, Subhashree , Panda
core +2 more sources
Direct Regioselective C-H Cyanation of Purines
Molecules, 2023 A direct regioselective C-H cyanation of purines was developed through a sequential triflic anhydride activation, nucleophilic cyanation with TMSCN, followed by a process of base-mediated elimination of triflous acid (CF3SO2H).
Luyong Li +6 more
doaj +1 more source
, 2020 An efficient method for the directing group controlled rhodium-catalyzed addition reaction of oxa/azabicylic alkenes with aromatic ketones and benzoic acids has been developed.
Keyang Zhang (8071334) +8 more
core +1 more source
Insights on tert-butyl alkylation effects on fluorobenzene
Scientific African, 2021 Directing effects of substituents on the benzene ring, ortho and para directors by electron donating groups and meta directors using electron withdrawing groups have been studied and reported widely. In particular and for many years, the directing effect
Lewis Mtashobya
doaj +1 more source
A Transient Directing Group Strategy Enables Enantioselective Reductive Heck Hydroarylation of Alkenes [PDF]
, 2019 Metal-coordinating directing groups have seen extensive use in the field of transition-metal-mediated functionalization of alkenes; however, their waste-generating installation and removal steps limit the efficiency and practicality of reactions that ...
Zi-Qi, Li +6 more
core +2 more sources