Results 61 to 70 of about 75,438 (278)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Analysis and optimization of an omnidirectional direction-finding system [PDF]

open access: yes, 1970
System determines the direction of arrival of an electromagnetic wave with the direction information in a readily usable form.
Beste, J. M., Graf, E. R.
core   +1 more source

Wireless capsule gastrointestinal endoscopy: direction of arrival estimation based localization survey [PDF]

open access: yes, 2017
One of the significant challenges in Capsule Endoscopy (CE) is to precisely determine the pathologies location. The localization process is primarily estimated using the received signal strength from sensors in the capsule system through its movement in ...
Ashour, Amira S.   +3 more
core   +1 more source

Noncircular coherent signal direction of arrival estimation for coprime array: A subspace‐based interpolation approach

open access: yesIET Radar, Sonar & Navigation
To address the array aperture loss caused by mainstream direction of arrival (DOA) estimation algorithms for coherent signals using matrix interpolation techniques, a non‐circular (NC) coherent signal direction‐finding method that fully utilises ...
Zihan Shen   +3 more
doaj   +1 more source

A high-resolution DOA estimation method for deep-sea multipath coherent channels [PDF]

open access: yesZhihui kongzhi yu fangzhen
Aiming at the problem of error in deep-sea DOA(Direction of Arrival, DOA) estimation based on plane wave sound field model, this paper establishes the array signal model of deep-sea DOA estimation under multipath channel based on ray theory.
CAO Yongjie, MAO Weining
doaj   +1 more source

Total Least Squares Method for Direction of Arrival Estimation [PDF]

open access: yesJisuanji gongcheng, 2019
In the Time Difference of Arrival(TDOA) positioning technology,when the position coordinates of the sensor have errors,the estimated value obtained by the Least Squares(LS) method no longer has the best unbiasedness,resulting in a decrease in the ...
WANG Hai, ZHANG Menghan, CUI Xunxue
doaj   +1 more source

High-Order Maximum Likelihood Methods for Direction of Arrival Estimation

open access: yesIEEE Open Journal of Signal Processing, 2021
It is shown that using high-order statistics (higher than two) is beneficial in subspace-based Direction Of Arrival (DOA) estimation methods. Particularly, the high-order MUltiple SIgnal Classification (MUSIC) method, also known as $ 2q$-MUSIC method ...
Mohammadhossein Barat   +2 more
doaj   +1 more source

Adaptive Measurement Matrix Design in Direction of Arrival Estimation

open access: yesIEEE Transactions on Signal Processing, 2022
Advances in compressed sensing (CS) theory have brought new perspectives to encoding and decoding of signals with sparse representations. The encoding strategies are determined by measurement matrices whose design is a critical aspect of the CS applications.
Berkan Kilic   +3 more
openaire   +4 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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