Results 71 to 80 of about 21,799 (306)

Nonlinear Sherman-type inequalities

open access: yesAdvances in Nonlinear Analysis, 2018
An important class of Schur-convex functions is generated by convex functions via the well-known Hardy–Littlewood–Pólya–Karamata inequality. Sherman’s inequality is a natural generalization of the HLPK inequality.
Niezgoda Marek
doaj   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Second-order mollified derivatives and optimization [PDF]

open access: yes
The class of strongly semicontinuous functions is considered. For these functions the notion of mollified derivatives, introduced by Ermoliev, Norkin and Wets, is extended to the second order.
Rocca Matteo   +2 more
core  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

On the Shape Differentiability of Objectives: A Lagrangian Approach and the Brinkman Problem

open access: yesAxioms, 2018
This paper establishes the shape derivative of geometry-dependent objective functions for use in constrained variational problems. Using a Lagrangian approach, our differentiablity result is based on the theorem of Delfour⁻Zolésio on ...
José Rodrigo González Granada   +2 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle   +4 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Sensitizers of the bacteriochlorin series: prospects of the usage in photodynamic therapy

open access: yesТонкие химические технологии, 2006
Materials concerning synthesis and chemical modification of the bacteriochlorophyll a for 10-15 years past were collected in this review. Effectiveness of the bacteriochlorin derivatives usage in photodynamic therapy was discussed.
А. M. Mironov, M. A. Grin
doaj  

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti   +5 more
wiley   +1 more source

Fast hyperparameter tuning using Bayesian optimization with directional derivatives

open access: yes, 2020
Fast hyperparameter tuning using Bayesian optimization with directional ...
TT Joy (14546552)   +3 more
core  

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